{"id":23373,"date":"2025-04-13T17:39:38","date_gmt":"2025-04-13T17:39:38","guid":{"rendered":"https:\/\/researchchemicalstore.eu\/?post_type=product&#038;p=23373"},"modified":"2026-02-02T10:02:24","modified_gmt":"2026-02-02T10:02:24","slug":"eskalin-fumarat","status":"publish","type":"product","link":"https:\/\/researchchemicalstore.eu\/cs\/produkt\/eskalin-fumarat\/","title":{"rendered":"Eskalin fumar\u00e1t"},"content":{"rendered":"<h1><strong>Eskalin fumar\u00e1t \u2013 inovativn\u00ed psychedelick\u00fd fenethylamin pro v\u011bdeck\u00fd v\u00fdzkum<\/strong><\/h1>\n<p><strong>N\u00e1zev produktu:<\/strong> Eskalin fumar\u00e1t<br \/>\n<strong>Cel\u00e9 jm\u00e9no:<\/strong> 3,5-dimethoxy-4-ethoxyfenethylamin fumar\u00e1t<br \/>\n<strong>Chemick\u00e1 t\u0159\u00edda:<\/strong> Psychedelick\u00fd fenethylamin<br \/>\n<strong>Molekul\u00e1rn\u00ed vzorec (fumar\u00e1tov\u00e1 s\u016fl):<\/strong> C12H19NO3 C4H4O4<br \/>\n<strong>Molekulov\u00e1 hmotnost:<\/strong> \u00b1 325,34 g\/mol<br \/>\n<strong>Vzhled:<\/strong> B\u00edl\u00fd a\u017e sv\u011btle \u017elut\u00fd pr\u00e1\u0161ek (krystalick\u00fd)<br \/>\n<strong>\u010cistota:<\/strong> \u2265 98% (testov\u00e1no pomoc\u00ed HPLC a NMR)<br \/>\n<strong>Synonyma:<\/strong> Eskalin hemi-fumar\u00e1t, 4-ethoxy-meskalin<\/p>\n<hr \/>\n<h2>\ud83e\uddec <strong>Co je escalin fumar\u00e1t?<\/strong><\/h2>\n<p>Escaline je <strong>psychedelick\u00fd fenethylamin<\/strong> a strukturn\u00ed analog meskalinu s <strong>ethoxylov\u00e1 skupina<\/strong> m\u00edsto methoxyskupiny v poloze 4. Fumar\u00e1tov\u00e1 verze (ve form\u011b soli) nab\u00edz\u00ed vylep\u0161en\u00e9 <strong>stabilita a rozpustnost<\/strong>, ide\u00e1ln\u00ed pro p\u0159esnou laboratorn\u00ed anal\u00fdzu.<\/p>\n<blockquote><p>\u26a0\ufe0f <em>Pouze pro analytick\u00fd a farmakologick\u00fd v\u00fdzkum. Nen\u00ed ur\u010deno k lidsk\u00e9 spot\u0159eb\u011b.<\/em><\/p><\/blockquote>\n<hr \/>\n<h2>\ud83d\udd2c <strong>Aplikace ve v\u00fdzkumu<\/strong><\/h2>\n<p>Escaline je vy\u0161et\u0159ov\u00e1n kv\u016fli sv\u00e9mu <strong>agonistick\u00fd \u00fa\u010dinek na serotonergn\u00ed receptory<\/strong> (zejm\u00e9na 5-HT2A) a jeho struktur\u00e1ln\u00ed podobnost s klasick\u00fdmi psychedeliky.<\/p>\n<h3>Mo\u017en\u00e9 aplikace:<\/h3>\n<ul>\n<li><strong>Studie vazby receptor\u016f<\/strong> v serotonergn\u00edch drah\u00e1ch<\/li>\n<li><strong>Neurochemick\u00e1 srovn\u00e1vac\u00ed studie<\/strong> s meskalinem, proskalinem a isoproskalinem<\/li>\n<li><strong>Farmakokinetick\u00e9 simulace<\/strong> a anal\u00fdzy SAR (vztah mezi strukturou a aktivitou)<\/li>\n<li><strong>Modelov\u00e1n\u00ed v\u011bdom\u00ed in vitro<\/strong> prost\u0159ednictv\u00edm bun\u011b\u010dn\u00fdch lini\u00ed a metod anal\u00fdzy receptor\u016f<\/li>\n<\/ul>\n<hr \/>\n<h2>\ud83e\uddea <strong>Pou\u017eit\u00ed a laboratorn\u00ed pokyny<\/strong><\/h2>\n<ul>\n<li><strong>Rozpustnost:<\/strong> Voln\u011b rozpustn\u00fd v ethanolu, DMSO; m\u00edrn\u011b rozpustn\u00fd ve vod\u011b<\/li>\n<li><strong>Doporu\u010den\u00e1 koncentrace (in vitro):<\/strong> 5\u201330 \u00b5M v z\u00e1vislosti na typu testu<\/li>\n<li><strong>Ulo\u017eit:<\/strong> Such\u00e9, vzduchot\u011bsn\u00e9 a p\u0159i teplot\u011b 2\u20138 \u00b0C<\/li>\n<li><strong>Formul\u00e1\u0159:<\/strong> Hemi-fumar\u00e1t (pom\u011br eskalinu a fumar\u00e1tu 1:0,5)<\/li>\n<li><strong>Doporu\u010den\u00e9 OOPP:<\/strong> Rukavice, ochrann\u00e9 br\u00fdle, pr\u00e1ce v prost\u0159ed\u00ed s ods\u00e1v\u00e1n\u00edm<\/li>\n<\/ul>\n<hr \/>\n<h2>\u274c <strong>Nev\u00fdhody a rizika<\/strong><\/h2>\n<p>P\u0159esto\u017ee je Escaline cenn\u00fd pro v\u011bdeck\u00fd v\u00fdzkum, existuj\u00ed ur\u010dit\u00e1 omezen\u00ed:<\/p>\n<ul>\n<li><strong>Omezen\u00fd v\u00fdzkum:<\/strong> Velmi m\u00e1lo dostupn\u00fdch recenzovan\u00fdch dat<\/li>\n<li><strong>Psychoaktivn\u00ed profil:<\/strong> Mo\u017en\u00fd siln\u00fd \u00fa\u010dinek v p\u0159\u00edpad\u011b n\u00e1hodn\u00e9 expozice<\/li>\n<li><strong>Legislativa:<\/strong> Mo\u017en\u00e1 nez\u00e1konn\u00e9 podle analogick\u00e9 legislativy (NL\/BE\/EU)<\/li>\n<li><strong>Citlivost struktury:<\/strong> Mal\u00e9 molekul\u00e1rn\u00ed zm\u011bny mohou dramaticky ovlivnit biologick\u00e9 reakce<\/li>\n<\/ul>\n<hr \/>\n<h2>\ud83d\udcca <strong>Anal\u00fdza vzorku v laborato\u0159i<\/strong><\/h2>\n<p><strong>K\u00f3d d\u00e1vky:<\/strong> ESC-FUM-2025-07<br \/>\n<strong>Testov\u00e1no:<\/strong> DeltaChem Scientifics BV<br \/>\n<strong>Anal\u00fdza dat:<\/strong> 2025-06-10<\/p>\n<table>\n<thead>\n<tr>\n<th>Metoda anal\u00fdzy<\/th>\n<th>V\u00fdsledek<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>HPLC<\/td>\n<td>\u010cistota 98,61 TP3T<\/td>\n<\/tr>\n<tr>\n<td>NMR spektroskopie<\/td>\n<td>Toto\u017enost potvrzena<\/td>\n<\/tr>\n<tr>\n<td>FTIR spektroskopie<\/td>\n<td>Funk\u010dn\u00ed skupiny podle<\/td>\n<\/tr>\n<tr>\n<td>GC-MS<\/td>\n<td>\u017d\u00e1dn\u00e9 ne\u010distoty nebyly zji\u0161t\u011bny<\/td>\n<\/tr>\n<tr>\n<td>T\u011b\u017ek\u00e9 kovy<\/td>\n<td>Nedetekovateln\u00e9 (&lt;0,01%)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<hr \/>\n<h2>\u2753 <strong>\u010casto kladen\u00e9 ot\u00e1zky (FAQ)<\/strong><\/h2>\n<h3>Co p\u0159esn\u011b Escaline d\u011bl\u00e1?<\/h3>\n<p>Escaline je pravd\u011bpodobn\u011b <strong>Agonista 5-HT2A receptoru<\/strong>, podobn\u011b jako meskalin, co\u017e vede ke zm\u011bn\u00e1m ve vn\u00edm\u00e1n\u00ed a v\u011bdom\u00ed. P\u0159esn\u00e1 farmakodynamika v\u0161ak st\u00e1le nen\u00ed zcela prozkoum\u00e1na.<\/p>\n<h3>Je Escaline v Nizozemsku leg\u00e1ln\u00ed?<\/h3>\n<p><strong>Mo\u017en\u00e1 ne.<\/strong> I kdy\u017e se to \u010dasto konkr\u00e9tn\u011b nezmi\u0148uje, m\u016f\u017ee to b\u00fdt <strong>analogick\u00e1 legislativa<\/strong> p\u00e1d. Doporu\u010duje se pr\u00e1vn\u00ed poradenstv\u00ed.<\/p>\n<h3>Je Escaline tot\u00e9\u017e co meskalin?<\/h3>\n<p><strong>\u017d\u00e1dn\u00fd.<\/strong> Je to analog: Escaline obsahuje <strong>ethoxylov\u00e1 skupina<\/strong> m\u00edsto 4-methoxy skupiny meskalinu, kter\u00e1 ovliv\u0148uje \u00fa\u010dinnost a vazebn\u00fd profil.<\/p>\n<h3>Mohu si Escaline vyzkou\u0161et nebo vyzkou\u0161et s\u00e1m\/sama?<\/h3>\n<p><strong>\u017d\u00e1dn\u00fd.<\/strong> Tento produkt je ur\u010den pouze k pou\u017eit\u00ed <strong>profesion\u00e1ln\u00ed laboratorn\u00ed pou\u017eit\u00ed<\/strong> a je <strong>nen\u00ed schv\u00e1leno pro lidskou spot\u0159ebu<\/strong>.<\/p>\n<h3>Pro\u010d se dod\u00e1v\u00e1 ve form\u011b fumar\u00e1tu?<\/h3>\n<p>The <strong>fumar\u00e1tov\u00e1 forma<\/strong> nab\u00eddky:<\/p>\n<ul>\n<li>Lep\u0161\u00ed <strong>chemick\u00e1 stabilita<\/strong><\/li>\n<li><strong>M\u00e9n\u011b hygroskopick\u00e9 chov\u00e1n\u00ed<\/strong><\/li>\n<li>Jednodu\u0161\u0161\u00ed <strong>\u0159\u00edzen\u00ed d\u00e1vkov\u00e1n\u00ed<\/strong> ve v\u00fdzkumn\u00e9m prost\u0159ed\u00ed<\/li>\n<\/ul>\n<hr \/>\n<h2>\u26a0\ufe0f <strong>Pr\u00e1vn\u00ed a bezpe\u010dnostn\u00ed prohl\u00e1\u0161en\u00ed<\/strong><\/h2>\n<p><strong>Nen\u00ed ur\u010deno ke konzumaci.<\/strong> Dostupn\u00e9 pouze pro akademick\u00e9 instituce, v\u00fdzkumn\u00e1 za\u0159\u00edzen\u00ed a akreditovan\u00e9 laborato\u0159e. Prodej nezletil\u00fdm osob\u00e1m je zak\u00e1z\u00e1n. V\u00fdrobce ani prodejce nenesou \u017e\u00e1dnou odpov\u011bdnost za zneu\u017eit\u00ed.<\/p>","protected":false},"excerpt":{"rendered":"<h3>Vlastnosti eskalinfumar\u00e1tu<\/h3>\n<p><strong>Synonymum:<\/strong> 3,5-dimethoxy-4-ethoxyfenethylamin fumar\u00e1t<br \/>\n<strong>\u010c\u00edslo CAS:<\/strong> 39201-82-6<br \/>\n<strong>Vzorec:<\/strong> 2-{3,5-dimethoxy-4-ethyloxyfenyl}ethan-1-amin fumar\u00e1t<br \/>\n<strong>Mol\u00e1rn\u00ed hmotnost:<\/strong> 341,4 g\/mol<br \/>\n<strong>\u010cistota:<\/strong> &gt;97%<\/p>","protected":false},"featured_media":28776,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[322,535,80],"product_tag":[326],"class_list":{"0":"post-23373","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-bijna-verboden","7":"product_cat-escaline","8":"product_cat-fenethylamine","9":"product_tag-nl","11":"first","12":"instock","13":"taxable","14":"shipping-taxable","15":"purchasable","16":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/product\/23373","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/comments?post=23373"}],"version-history":[{"count":3,"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/product\/23373\/revisions"}],"predecessor-version":[{"id":26544,"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/product\/23373\/revisions\/26544"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/media\/28776"}],"wp:attachment":[{"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/media?parent=23373"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/product_brand?post=23373"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/product_cat?post=23373"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/product_tag?post=23373"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}