{"id":23461,"date":"2025-04-13T17:39:49","date_gmt":"2025-04-13T17:39:49","guid":{"rendered":"https:\/\/researchchemicalstore.eu\/?post_type=product&p=23461"},"modified":"2026-02-02T09:48:08","modified_gmt":"2026-02-02T09:48:08","slug":"4-ho-sladovy-fumarat","status":"publish","type":"product","link":"https:\/\/researchchemicalstore.eu\/cs\/produkt\/4-ho-sladovy-fumarat\/","title":{"rendered":"4-HO-MALT fumar\u00e1t"},"content":{"rendered":"

4-HO-MALT fumar\u00e1t \u2013 v\u011bdeck\u00fd popis produktu<\/strong><\/h3>\n

Obecn\u00e9 informace<\/strong><\/h4>\n

4-HO-MALT (4-hydroxy-N-methyl-N-allyltryptamin) fumar\u00e1t je v\u00fdzkumn\u00e1 chemik\u00e1lie t\u0159\u00eddy tryptamin\u016f, strukturn\u011b p\u0159\u00edbuzn\u00e1 slou\u010denin\u00e1m, jako je psilocin a 4-HO-MET. Tato slou\u010denina se prod\u00e1v\u00e1 exkluzivn\u011b pro\u00a0v\u011bdeck\u00fd v\u00fdzkum<\/strong>\u00a0a je\u00a0nen\u00ed ur\u010deno k lidsk\u00e9 spot\u0159eb\u011b<\/strong>.<\/p>\n

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Technick\u00e9 specifikace<\/strong><\/h4>\n
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    Chemick\u00fd n\u00e1zev:<\/strong>\u00a04-Hydroxy-N-methyl-N-allyltryptamin fumar\u00e1t<\/p>\n<\/li>\n

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    \u010c\u00edslo CAS:<\/strong>\u00a0[Pokud je k dispozici]<\/p>\n<\/li>\n

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    Molekul\u00e1rn\u00ed vzorec:<\/strong>\u00a0C\u2081\u2085H\u2082\u2080N\u2082O\u2082 \u00b7 C\u2084H\u2084O\u2084<\/p>\n<\/li>\n

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    Molekulov\u00e1 hmotnost:<\/strong>\u00a0350,37 g\/mol<\/p>\n<\/li>\n

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    \u010cistota:<\/strong>\u00a0\u226598% (ov\u011b\u0159eno HPLC-MS)<\/p>\n<\/li>\n

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    Vzhled:<\/strong>\u00a0B\u00edl\u00fd a\u017e sv\u011btle \u017elut\u00fd krystalick\u00fd pr\u00e1\u0161ek<\/p>\n<\/li>\n

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    Rozpustnost:<\/strong>\u00a0Rozpustn\u00fd ve vod\u011b (20 mg\/ml) a ethanolu<\/p>\n<\/li>\n

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    Stabilita:<\/strong>\u00a0>12 m\u011bs\u00edc\u016f p\u0159i skladov\u00e1n\u00ed pod -20 \u00b0C ve vzduchot\u011bsn\u00e9m obalu<\/p>\n<\/li>\n<\/ul>\n

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    V\u011bdeck\u00e9 aplikace<\/strong><\/h3>\n

    4-HO-MALT fumar\u00e1t se pou\u017e\u00edv\u00e1 ve v\u00fdzkumu pro:<\/p>\n

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    1. \n

      Neurofarmakologick\u00e9 studie:<\/strong><\/p>\n

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        Vazebn\u00e9 vlastnosti k serotoninov\u00fdm (5-HT\u2082A\/5-HT\u2081A) receptor\u016fm<\/p>\n<\/li>\n

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        Srovn\u00e1vac\u00ed studie s klasick\u00fdmi psychedeliky<\/p>\n<\/li>\n<\/ul>\n<\/li>\n

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        Behavior\u00e1ln\u00ed v\u00fdzkum:<\/strong><\/p>\n

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          Vlivy na senzorick\u00e9 zpracov\u00e1n\u00ed u zv\u00ed\u0159ec\u00edch model\u016f<\/p>\n<\/li>\n

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          Testov\u00e1n\u00ed chov\u00e1n\u00ed souvisej\u00edc\u00edho s \u00fazkost\u00ed v otev\u0159en\u00e9m poli<\/p>\n<\/li>\n<\/ul>\n<\/li>\n

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          Metabolick\u00e9 studie:<\/strong><\/p>\n

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            Studie jatern\u00edho metabolismu in vitro<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n

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            Experiment\u00e1ln\u00ed parametry<\/strong><\/h3>\n

            D\u00e1vkov\u00e1n\u00ed (pro preklinick\u00e9 studie)<\/strong><\/h4>\n
            \n\n\n\n\n\n\n\n
            Zp\u016fsob pod\u00e1n\u00ed<\/th>\nTestovan\u00e1 koncentrace<\/th>\nRozpou\u0161t\u011bdlo<\/th>\n<\/tr>\n<\/thead>\n
            \u00dastn\u00ed<\/td>\n5\u201315 mg\/kg<\/td>\nPBS pufr<\/td>\n<\/tr>\n
            Intraperitone\u00e1ln\u00ed<\/td>\n2\u20138 mg\/kg<\/td>\nSteriln\u00ed H\u2082O<\/td>\n<\/tr>\n
            In vitro<\/td>\n1\u2013100 \u03bcM<\/td>\nDMSO <0,1%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

            Pozn\u00e1mka: D\u00e1vkov\u00e1n\u00ed je zalo\u017eeno na strukturn\u011b p\u0159\u00edbuzn\u00fdch slou\u010denin\u00e1ch. V\u017edy prov\u00e1d\u011bjte pilotn\u00ed studie.<\/em><\/p>\n

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            Bezpe\u010dnostn\u00ed protokol<\/strong><\/h3>\n

            Potenci\u00e1ln\u00ed rizika<\/strong><\/h4>\n
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              Akutn\u00ed toxicita:<\/strong>\u00a0LD\u2085\u2080 nebyla stanovena \u2013 pou\u017eijte princip ALARA<\/p>\n<\/li>\n

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              Ne\u017e\u00e1douc\u00ed \u00fa\u010dinky:<\/strong><\/p>\n

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                Zv\u00fd\u0161en\u00e1 pohybov\u00e1 aktivita p\u0159i n\u00edzk\u00fdch d\u00e1vk\u00e1ch<\/p>\n<\/li>\n

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                Katalepsie p\u0159i vy\u0161\u0161\u00edch koncentrac\u00edch<\/p>\n<\/li>\n<\/ul>\n<\/li>\n

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                Nebezpe\u010d\u00ed prachu:<\/strong>\u00a0P\u0159i manipulaci s pr\u00e1\u0161kem v\u017edy pou\u017e\u00edvejte masku P2<\/p>\n<\/li>\n<\/ul>\n

                Skladovac\u00ed podm\u00ednky<\/strong><\/h4>\n
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                  Skladujte p\u0159i teplot\u011b -20 \u00b0C v argonov\u00e9 atmosf\u00e9\u0159e<\/p>\n<\/li>\n

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                  Pou\u017e\u00edvejte lahvi\u010dky z jantarov\u00e9ho skla<\/p>\n<\/li>\n

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                  Trvanlivost: 24 m\u011bs\u00edc\u016f p\u0159i spr\u00e1vn\u00e9m skladov\u00e1n\u00ed<\/p>\n<\/li>\n<\/ul>\n

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                  Analytick\u00e1 data<\/strong><\/h3>\n

                  Kontrola kvality (\u0161ar\u017ee XYZ-123)<\/strong><\/h4>\n
                  \n\n\n\n\n\n\n\n
                  Test<\/th>\nV\u00fdsledek<\/th>\nMetoda<\/th>\n<\/tr>\n<\/thead>\n
                  \u010cistota<\/td>\n98.7%<\/td>\nHPLC-UV (254 nm)<\/td>\n<\/tr>\n
                  T\u011b\u017ek\u00e9 kovy<\/td>\n<10 ppm<\/td>\nICP-MS<\/td>\n<\/tr>\n
                  Obsah vody<\/td>\n0.8%<\/td>\nKarl Fischer<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
                  \n

                  \u010casto kladen\u00e9 ot\u00e1zky (FAQ)<\/strong><\/h3>\n

                  1. Je tato l\u00e1tka v EU regulov\u00e1na?<\/strong><\/p>\n

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                    Status se li\u0161\u00ed v jednotliv\u00fdch \u010dlensk\u00fdch st\u00e1tech. V Nizozemsku m\u016f\u017ee spadat pod z\u00e1kon o opiu. Informujte se v m\u00edstn\u00edch p\u0159edpisech.<\/p>\n<\/li>\n<\/ul>\n

                    2. Kter\u00e9 analytick\u00e9 metody se doporu\u010duj\u00ed?<\/strong><\/p>\n

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                    • \n

                      HPLC-MS pro kvantifikaci<\/p>\n<\/li>\n

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                      NMR (\u00b9H\/\u00b9\u00b3C) pro potvrzen\u00ed struktury<\/p>\n<\/li>\n<\/ul>\n

                      3. Mohu obdr\u017eet bezpe\u010dnostn\u00ed list materi\u00e1lu?<\/strong><\/p>\n

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                      • \n

                        Ano, pro akademick\u00e9 instituce je k dispozici roz\u0161\u00ed\u0159en\u00fd bezpe\u010dnostn\u00ed list.<\/p>\n<\/li>\n<\/ul>\n

                        4. Jak\u00e1 je stabilita v roztoku?<\/strong><\/p>\n

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                        • \n

                          Skladujte v PBS a\u017e 48 hodin p\u0159i 4 \u00b0C. Pro del\u0161\u00ed skladov\u00e1n\u00ed zmrazte p\u0159i -80 \u00b0C.<\/p>\n<\/li>\n<\/ul>\n

                          \n

                          Informace o objedn\u00e1vce<\/strong><\/h3>\n
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                            Minim\u00e1ln\u00ed objedn\u00e1vka:<\/strong>\u00a0100 mg<\/p>\n<\/li>\n

                          • \n

                            Obal:<\/strong>\u00a0Pod argonem v jantarov\u00e9 HPLC lahvi\u010dce<\/p>\n<\/li>\n

                          • \n

                            Doprava:<\/strong>\u00a0Chlazen\u00e1 p\u0159eprava s kostkami ledu<\/p>\n<\/li>\n<\/ul>\n

                            UPOZORN\u011aN\u00cd: Tento produkt je ur\u010den pouze pro v\u00fdzkumn\u00e9 pou\u017eit\u00ed kvalifikovan\u00fdm person\u00e1lem v akreditovan\u00fdch laborato\u0159\u00edch. Nen\u00ed ur\u010den k diagnostick\u00e9mu ani terapeutick\u00e9mu pou\u017eit\u00ed.<\/em><\/p>\n

                            Pro v\u00fdzkumnou spolupr\u00e1ci nebo hromadn\u00e9 objedn\u00e1vky kontaktujte pros\u00edm na\u0161e v\u011bdeck\u00e9 odd\u011blen\u00ed.<\/p>","protected":false},"excerpt":{"rendered":"

                            4-HO-MALT fumar\u00e1t \u2013 v\u011bdeck\u00fd popis produktu Obecn\u00e9 informace 4-HO-MALT (4-hydroxy-N-methyl-N-allyltryptamin) fumar\u00e1t je v\u00fdzkumn\u00e1 chemik\u00e1lie t\u0159\u00eddy tryptamin\u016f, strukturn\u011b p\u0159\u00edbuzn\u00e1 l\u00e1tk\u00e1m<\/p>","protected":false},"featured_media":28703,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[543,381],"product_tag":[326],"class_list":{"0":"post-23461","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-4-ho-malt","7":"product_cat-tryptamines","8":"product_tag-nl","10":"first","11":"instock","12":"taxable","13":"shipping-taxable","14":"purchasable","15":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/product\/23461","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/comments?post=23461"}],"version-history":[{"count":3,"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/product\/23461\/revisions"}],"predecessor-version":[{"id":26630,"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/product\/23461\/revisions\/26630"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/media\/28703"}],"wp:attachment":[{"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/media?parent=23461"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/product_brand?post=23461"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/product_cat?post=23461"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/cs\/wp-json\/wp\/v2\/product_tag?post=23461"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}