{"id":23358,"date":"2025-04-13T17:39:37","date_gmt":"2025-04-13T17:39:37","guid":{"rendered":"https:\/\/researchchemicalstore.eu\/?post_type=product&p=23358"},"modified":"2025-10-23T01:15:38","modified_gmt":"2025-10-23T01:15:38","slug":"dmxe-40-mg-en-pastillas-de-desoximetoxetamina","status":"publish","type":"product","link":"https:\/\/researchchemicalstore.eu\/es\/producto\/dmxe-40-mg-en-pastillas-de-desoximetoxetamina\/","title":{"rendered":"Pellets de DMXE de 40 mg (desoximetoxetamina)"},"content":{"rendered":"

DMXE (desoximetoxetamina) en pastillas de 40 mg: documentaci\u00f3n cient\u00edfica del producto<\/span><\/span><\/strong><\/h3>\n

\ud83d\udd2cEspecificaciones qu\u00edmicas<\/span><\/span><\/strong><\/h4>\n

El DMXE (2\u2032-Oxo-PCE-d10) es una sustancia qu\u00edmica de investigaci\u00f3n perteneciente a la clase de las arilciclohexilaminas, estructuralmente relacionada con la MXE (metoxetamina) y la ketamina. Estos gr\u00e1nulos est\u00e1n formulados para la investigaci\u00f3n cient\u00edfica de precisi\u00f3n.<\/span><\/span><\/p>\n

Par\u00e1metros b\u00e1sicos:<\/span><\/span><\/em><\/p>\n

    \n
  • \n

    Nombre IUPAC<\/span><\/span><\/strong> : 2-(3,4-Dimetilfenil)-2-(etilamino)ciclohexanona<\/span><\/span><\/p>\n<\/li>\n

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    F\u00f3rmula molecular<\/span><\/span><\/strong> : C\u2081\u2086H\u2082\u2083NO<\/span><\/span><\/p>\n<\/li>\n

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    Peso molecular<\/span><\/span><\/strong> : 245,36 g\/mol<\/span><\/span><\/p>\n<\/li>\n

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    Pureza<\/span><\/span><\/strong> : \u226598% (an\u00e1lisis GC-MS)<\/span><\/span><\/p>\n<\/li>\n

  • \n

    Forma<\/span><\/span><\/strong> : Balines redondos de 4 mm de di\u00e1metro.<\/span><\/span><\/p>\n<\/li>\n

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    Color<\/span><\/span><\/strong> : Beige claro a blanco<\/span><\/span><\/p>\n<\/li>\n

  • \n

    Solubilidad<\/span><\/span><\/strong> : 15 mg\/ml en agua (a 25\u00b0C)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

    \ud83e\uddeaAplicaciones cient\u00edficas<\/span><\/span><\/strong><\/h4>\n
      \n
    1. \n

      Investigaci\u00f3n neurofarmacol\u00f3gica<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

        \n
      • \n

        Estudios de antagonismo del receptor NMDA<\/span><\/span><\/p>\n<\/li>\n

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        Ensayos de interacci\u00f3n del receptor Sigma-1<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

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        Neurociencia del comportamiento<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

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        • \n

          Efectos sobre la conducta de aprendizaje en animales de laboratorio<\/span><\/span><\/p>\n<\/li>\n

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          Efectos disociativos dependientes de la dosis<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

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          Psicofarmacolog\u00eda<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

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          • \n

            Estudios comparativos con disociativos relacionados<\/span><\/span><\/p>\n<\/li>\n

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            Investigaci\u00f3n sobre los efectos neuropl\u00e1sticos<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n

            \u2696\ufe0fProtocolos de investigaci\u00f3n recomendados<\/span><\/span><\/strong><\/h4>\n

            Pautas experimentales:<\/span><\/span><\/em><\/p>\n

            \n\n\n\n\n\n\n\n
            Modelo<\/span><\/span><\/th>\nDosificaci\u00f3n<\/span><\/span><\/th>\nFrecuencia<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
            In vitro<\/span><\/span><\/td>\n10-50 \u03bcM<\/span><\/span><\/td>\nExposici\u00f3n \u00fanica<\/span><\/span><\/td>\n<\/tr>\n
            peque\u00f1os roedores<\/span><\/span><\/td>\n5-20 mg\/kg<\/span><\/span><\/td>\n1x\/d\u00eda (m\u00e1ximo 3 d\u00edas)<\/span><\/span><\/td>\n<\/tr>\n
            Primates<\/span><\/span><\/td>\n1-5 mg\/kg<\/span><\/span><\/td>\nDosis \u00fanica<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

            *Nota: Farmacocin\u00e9tica no lineal por encima de 25 mg\/kg*<\/span><\/span><\/p>\n

            \u26a0\ufe0fPerfil de seguridad y gesti\u00f3n de riesgos<\/span><\/span><\/strong><\/h4>\n
              \n
            1. \n

              Datos toxicol\u00f3gicos<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

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              • \n

                LD\u2085\u2080 (rata, oral): 320 mg\/kg<\/span><\/span><\/p>\n<\/li>\n

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                NOAEL: 5 mg\/kg\/d\u00eda (estudio de 7 d\u00edas)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

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                Espectro de efectos secundarios<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

                  \n
                • \n

                  <10 mg: Efectos conductuales sutiles<\/span><\/span><\/p>\n<\/li>\n

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                  10-30 mg: Incoordinaci\u00f3n motora<\/span><\/span><\/p>\n<\/li>\n

                • \n
                  \n

                  30 mg: Posible depresi\u00f3n respiratoria<\/span><\/span><\/p>\n<\/blockquote>\n<\/li>\n<\/ul>\n<\/li>\n

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                  Interacciones cr\u00edticas<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

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                  • \n

                    Peligroso<\/span><\/span><\/strong> : Opioides, GABA\u00e9rgicos<\/span><\/span><\/p>\n<\/li>\n

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                    Arriesgado<\/span><\/span><\/strong> : Estimulantes, inhibidores de la MAO<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n

                    \ud83d\udccaControl de calidad y datos anal\u00edticos<\/span><\/span><\/strong><\/h4>\n
                      \n
                    • \n

                      Pureza de HPLC<\/span><\/span><\/strong> : 98,5% (columna C18, 70:30 H\u2082O:MeCN)<\/span><\/span><\/p>\n<\/li>\n

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                      Uniformidad<\/span><\/span><\/strong> : \u00b15% desviaci\u00f3n de peso (n=20 pellets)<\/span><\/span><\/p>\n<\/li>\n

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                      Tiempo de desintegraci\u00f3n<\/span><\/span><\/strong> : <15 minutos (en jugo g\u00e1strico simult\u00e1neo)<\/span><\/span><\/p>\n<\/li>\n

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                      Datos de estabilidad<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

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                        Vida \u00fatil: 24 meses a 15-25\u00b0C<\/span><\/span><\/p>\n<\/li>\n

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                        Sensibilidad a la humedad: <0,5% aumento de peso (93% HR)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

                        \u2753Preguntas frecuentes sobre investigaci\u00f3n<\/span><\/span><\/strong><\/h4>\n

                        Q1: \u00bfCu\u00e1l es el mecanismo de acci\u00f3n?<\/span><\/span><\/strong>
                        \n A: Antagonismo primario del receptor NMDA con inhibici\u00f3n secundaria de la recaptaci\u00f3n de dopamina.<\/span><\/span><\/p>\n

                        P2: \u00bfC\u00f3mo se compara la potencia con la ketamina?<\/span><\/span><\/strong>
                        \n R: ~0,6 veces la potencia de la ketamina, pero con una vida media m\u00e1s larga (4-6 horas).<\/span><\/span><\/p>\n

                        P3: \u00bfExisten riesgos neurot\u00f3xicos?<\/span><\/span><\/strong>
                        \n A: No se observaron lesiones de Olney a <50 mg\/kg (estudio en ratas).<\/span><\/span><\/p>\n

                        Q4: \u00bfCu\u00e1l es el m\u00e9todo de almacenamiento \u00f3ptimo?<\/span><\/span><\/strong>
                        \n A: En el embalaje original a 15-25\u00b0C, protegido de la humedad.<\/span><\/span><\/p>\n

                        \ud83d\udcccLimitaciones de la investigaci\u00f3n<\/span><\/span><\/strong><\/h4>\n
                          \n
                        • \n

                          Datos limitados sobre la administraci\u00f3n cr\u00f3nica<\/span><\/span><\/p>\n<\/li>\n

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                          Efectos desconocidos sobre la transmisi\u00f3n del glutamato<\/span><\/span><\/p>\n<\/li>\n

                        • \n

                          Biotransformaci\u00f3n variable entre especies<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                          \ud83d\udd0dConclusi\u00f3n para los investigadores<\/span><\/span><\/strong><\/h4>\n

                          Los gr\u00e1nulos de DMXE de 40 mg ofrecen una formulaci\u00f3n estandarizada para la investigaci\u00f3n disociativa precisa, con una administraci\u00f3n de dosis uniforme y buena estabilidad. Su presentaci\u00f3n en gr\u00e1nulos facilita la administraci\u00f3n cuantitativa en estudios con animales.<\/span><\/span><\/p>\n

                          Aviso cient\u00edfico: Este producto est\u00e1 destinado exclusivamente a la investigaci\u00f3n in vitro y a estudios precl\u00ednicos autorizados. No apto para uso humano. Todos los experimentos deben cumplir con las directrices \u00e9ticas y las normativas locales aplicables. Tenga en cuenta la situaci\u00f3n especial de las sustancias psicoactivas en investigaci\u00f3n en su jurisdicci\u00f3n.<\/span><\/span><\/em><\/p>","protected":false},"excerpt":{"rendered":"

                          Caracter\u00edsticas DMXE<\/span><\/span><\/span><\/span><\/h3>\n

                          Sin\u00f3nimo:<\/span><\/span><\/span><\/span><\/strong> clorhidrato de desoximetoxetamina <\/span><\/span><\/span><\/span>
                          \nN\u00famero CAS:<\/span><\/span><\/span><\/span><\/strong> 681440-83-5 <\/span><\/span><\/span><\/span>
                          \nF\u00f3rmula:<\/span><\/span><\/span><\/span><\/strong> 5-dehidro-1,3-quinodimetano <\/span><\/span><\/span><\/span>
                          \nMasa molar:<\/span><\/span><\/span><\/span><\/strong> 103,14 g\/mol <\/span><\/span><\/span><\/span>
                          \nPureza:<\/span><\/span><\/span><\/span><\/strong> >97%<\/span><\/span><\/span><\/span><\/p>","protected":false},"featured_media":28769,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[71,406,429,324],"product_tag":[326],"class_list":{"0":"post-23358","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-arylcyclohexylamine","7":"product_cat-dmxe","8":"product_cat-dmxe-pellets","9":"product_cat-pellets-for-pellet","10":"product_tag-nl","12":"first","13":"instock","14":"taxable","15":"shipping-taxable","16":"purchasable","17":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/product\/23358","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/comments?post=23358"}],"version-history":[{"count":5,"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/product\/23358\/revisions"}],"predecessor-version":[{"id":28083,"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/product\/23358\/revisions\/28083"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/media\/28769"}],"wp:attachment":[{"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/media?parent=23358"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/product_brand?post=23358"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/product_cat?post=23358"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/product_tag?post=23358"}],"curies":[{"name":"gracias","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}