{"id":23655,"date":"2025-04-13T17:40:11","date_gmt":"2025-04-13T17:40:11","guid":{"rendered":"https:\/\/researchchemicalstore.eu\/?post_type=product&p=23655"},"modified":"2025-10-22T14:57:47","modified_gmt":"2025-10-22T14:57:47","slug":"granulos-de-idra-21-de-10-mg","status":"publish","type":"product","link":"https:\/\/researchchemicalstore.eu\/es\/producto\/granulos-de-idra-21-de-10-mg\/","title":{"rendered":"Perdigones IDRA-21 de 10 mg"},"content":{"rendered":"

Pastillas IDRA-21 de 10 mg: descripci\u00f3n cient\u00edfica y manual del usuario<\/span><\/span><\/strong><\/h3>\n

Descripci\u00f3n del Producto<\/span><\/span><\/strong><\/h4>\n

IDRA-21 (gr\u00e1nulos de 10 mg)<\/span><\/span><\/strong> \u00a0es un potencial\u00a0 <\/span><\/span>Potenciador del receptor AMPA<\/span><\/span><\/strong> \u00a0perteneciente a la clase de\u00a0 <\/span><\/span>productos qu\u00edmicos de investigaci\u00f3n nootr\u00f3picos y neuroprotectores<\/span><\/span><\/strong> . Act\u00faa mejorando la se\u00f1alizaci\u00f3n inducida por glutamato en el cerebro, lo que puede conducir a una mejor funci\u00f3n cognitiva, neuroplasticidad y potencialmente neurorrecuperaci\u00f3n.<\/span><\/span><\/p>\n

Estos pellets son\u00a0 <\/span><\/span>altamente puro (\u226598%)<\/span><\/span><\/strong> , dosificado estandarizado y destinado \u00fanicamente para\u00a0 <\/span><\/span>investigaci\u00f3n cient\u00edfica y estudios precl\u00ednicos<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n

\n

Usos y aplicaciones<\/span><\/span><\/strong><\/h3>\n

Se est\u00e1 estudiando el IDRA-21 por sus posibles efectos en:<\/span><\/span><\/p>\n

    \n
  1. \n

    Mejora cognitiva<\/span><\/span><\/strong> \u00a0\u2013 Puede aumentar el estado de alerta, la capacidad de aprendizaje y la consolidaci\u00f3n de la memoria.<\/span><\/span><\/p>\n<\/li>\n

  2. \n

    Neuroprotecci\u00f3n<\/span><\/span><\/strong> \u00a0\u2013 Potencial efecto protector en enfermedades neurodegenerativas (p.ej. Alzheimer, ictus).<\/span><\/span><\/p>\n<\/li>\n

  3. \n

    Recuperaci\u00f3n neurol\u00f3gica<\/span><\/span><\/strong> \u00a0\u2013 Puede promover la plasticidad sin\u00e1ptica despu\u00e9s de una lesi\u00f3n cerebral.<\/span><\/span><\/p>\n<\/li>\n

  4. \n

    Investigaci\u00f3n cient\u00edfica<\/span><\/span><\/strong> \u00a0\u2013 Estudio de la modulaci\u00f3n del receptor AMPA y la se\u00f1alizaci\u00f3n del glutamato.<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

    \u26a0\u00a0No aprobado para uso humano ni veterinario. Solo para estudios precl\u00ednicos in vitro y controlados.<\/span><\/span><\/strong><\/p>\n

    \n

    Pautas de dosificaci\u00f3n y seguridad<\/span><\/span><\/strong><\/h3>\n
      \n
    • \n

      Dosis en investigaci\u00f3n (in vitro\/precl\u00ednica): <\/span><\/span><\/strong>\u00a05\u201320 mg\/kg<\/span><\/span><\/strong> \u00a0(dependiendo del modelo).<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Soluci\u00f3n de pellets:<\/span><\/span><\/strong> \u00a0Puede disolverse en\u00a0 <\/span><\/span>agua destilada o DMSO<\/span><\/span><\/strong> \u00a0para experimentos.<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Administraci\u00f3n:<\/span><\/span><\/strong> \u00a0Por v\u00eda oral (modelos animales) o directamente en cultivos celulares.<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Frecuencia:<\/span><\/span><\/strong> \u00a0Dosis \u00fanica para efecto agudo; los estudios a largo plazo requieren un seguimiento cuidadoso.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

      \ud83d\udea8\u00a0N\u00d3TESE BIEN:<\/span><\/span><\/strong><\/p>\n

        \n
      • \n

        Sin aplicaci\u00f3n humana<\/span><\/span><\/strong> \u00a0\u2013 No hay datos de seguridad para uso humano.<\/span><\/span><\/p>\n<\/li>\n

      • \n

        Dosis altas pueden causar neuroexcitotoxicidad.<\/span><\/span><\/strong><\/p>\n<\/li>\n

      • \n

        Evitar la combinaci\u00f3n con otros moduladores de glutamato.<\/span><\/span><\/strong><\/p>\n<\/li>\n<\/ul>\n

        \n

        Desventajas y riesgos<\/span><\/span><\/strong><\/h3>\n
          \n
        • \n

          Sobreestimulaci\u00f3n de las neuronas<\/span><\/span><\/strong> \u00a0(riesgo de excitotoxicidad en caso de sobredosis).<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Posible ansiedad o agitaci\u00f3n<\/span><\/span><\/strong> \u00a0en modelos susceptibles.<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Datos limitados a largo plazo<\/span><\/span><\/strong> \u00a0sobre la tolerancia y los efectos adversos.<\/span><\/span><\/p>\n<\/li>\n

        • \n

          No apto para uso cr\u00f3nico.<\/span><\/span><\/strong> \u00a0sin estudios extensos de toxicidad.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

          \n

          Preguntas frecuentes (FAQ)<\/span><\/span><\/strong><\/h3>\n

          1. \u00bfEs legal el IDRA-21 en los Pa\u00edses Bajos?<\/span><\/span><\/strong><\/h4>\n

          S\u00ed, pero s\u00f3lo para\u00a0 <\/span><\/span>investigaci\u00f3n cient\u00edfica<\/span><\/span><\/strong> . No est\u00e1 contemplado en la Ley del Opio, pero tampoco est\u00e1 aprobado como medicamento.<\/span><\/span><\/p>\n

          2. \u00bfC\u00f3mo funciona exactamente IDRA-21?<\/span><\/span><\/strong><\/h4>\n

          \u00c9l\u00a0 <\/span><\/span>mejora la respuesta del receptor AMPA<\/span><\/span><\/strong> , lo que hace que la se\u00f1alizaci\u00f3n del glutamato sea m\u00e1s prolongada e intensa. Esto puede mejorar la comunicaci\u00f3n sin\u00e1ptica.<\/span><\/span><\/p>\n

          3. \u00bfSe puede comparar IDRA-21 con otros nootr\u00f3picos?<\/span><\/span><\/strong><\/h4>\n

          Tiene un mecanismo de acci\u00f3n \u00fanico, pero\u00a0 <\/span><\/span>objetivos similares a los racetams o ampaquinas<\/span><\/span><\/strong> \u00a0(por ejemplo Sunifiram).<\/span><\/span><\/p>\n

          4. \u00bfExisten interacciones conocidas?<\/span><\/span><\/strong><\/h4>\n
            \n
          • \n

            antagonistas de NMDA<\/span><\/span><\/strong> \u00a0(p. ej. memantina) \u2013 Efectos potencialmente adversos.<\/span><\/span><\/p>\n<\/li>\n

          • \n

            Agentes GABA\u00e9rgicos<\/span><\/span><\/strong> \u00a0(por ejemplo, benzodiazepinas): pueden reducir los efectos ansiol\u00edticos.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

            \n

            Informe de laboratorio y control de calidad<\/span><\/span><\/strong><\/h3>\n
              \n
            • \n

              An\u00e1lisis HPLC: <\/span><\/span><\/strong>\u00a0\u226598% pureza<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n<\/li>\n

            • \n

              No se detectan metales pesados ni residuos de disolventes.<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Formulaci\u00f3n de pellets homog\u00e9neos<\/span><\/span><\/strong> \u00a0para una dosificaci\u00f3n consistente.<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Certificaci\u00f3n de lotes<\/span><\/span><\/strong> \u00a0Disponible para instituciones de investigaci\u00f3n.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

              \n

              Escenarios de investigaci\u00f3n recomendados<\/span><\/span><\/strong><\/h3>\n
                \n
              1. \n

                Estudios cognitivos<\/span><\/span><\/strong> \u00a0\u2013 Efectos sobre la memoria y el aprendizaje en modelos animales.<\/span><\/span><\/p>\n<\/li>\n

              2. \n

                Investigaci\u00f3n neuroprotectora<\/span><\/span><\/strong> \u00a0\u2013 Papel potencial en la lesi\u00f3n isqu\u00e9mica (modelos de accidente cerebrovascular).<\/span><\/span><\/p>\n<\/li>\n

              3. \n

                Electrofisiolog\u00eda<\/span><\/span><\/strong> \u00a0\u2013 Mediciones de la respuesta del receptor AMPA en cultivos neuronales.<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

                \ud83d\udd2c\u00a0Solo para uso controlado en laboratorio. \u00a1No uso recreativo!<\/span><\/span><\/strong><\/p>\n

                ","protected":false},"excerpt":{"rendered":"

                Propiedades de los pellets IDRA-21<\/span><\/span><\/h3>\n

                Sin\u00f3nimo<\/span><\/span><\/strong> : 1,1-di\u00f3xido de 7-cloro-3-metil-3,4-dihidro-2H-1,2,4-benzotiadiazina <\/span><\/span>
                \nCAS <\/span><\/span><\/strong> N\u00famero<\/span><\/span><\/strong> : 22503-72-6 <\/span><\/span>
                \nF\u00f3rmula<\/span><\/span><\/strong> :C8H9ClN2O2S <\/span><\/span>
                \nMasa molar<\/span><\/span><\/strong> :232,6 g\/mol <\/span><\/span>
                \nPureza<\/span><\/span><\/strong> : >97%<\/span><\/span><\/p>","protected":false},"featured_media":28802,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[548,549,330,324],"product_tag":[326],"class_list":["post-23655","product","type-product","status-publish","has-post-thumbnail","product_cat-idra-21","product_cat-idra-21-pellets","product_cat-nootropics","product_cat-pellets-for-pellet","product_tag-nl","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/product\/23655","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/comments?post=23655"}],"version-history":[{"count":5,"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/product\/23655\/revisions"}],"predecessor-version":[{"id":28058,"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/product\/23655\/revisions\/28058"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/media\/28802"}],"wp:attachment":[{"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/media?parent=23655"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/product_brand?post=23655"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/product_cat?post=23655"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/es\/wp-json\/wp\/v2\/product_tag?post=23655"}],"curies":[{"name":"gracias","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}