Tropakaiin HCl

Product Definition: Tropacocaine HCl (Research Chemical)

Keemiline nimetus:  Tropacocaine hydrochloride
Sünonüümid:  Tropacocaine HCl, Benzoylecgonine methyl ester
Molekulaarne valem:  C₁₅H₁₉NO₂•HCl
Molekulaarmass:  281.78 g/mol
CASi nr:  537-26-8
Välimus:  Valge kristalliline pulber
Puhtus:  ≥98% (HPLC-ga kontrollitud)
Lahustuvus:  50 mg/ml vees

Kirjeldus ja farmakoloogia:
Tropacocaine is a naturally occurring cocaine analog with:
✔Local anesthetic effects
✔Stimulant properties
✔Shorter duration of action than cocaine (1-2 hours)
✔More selective noradrenaline reuptake inhibition

Teadustöö rakendused:

1. Neuroteaduslikud uuringud:

   • Dopamine transporter studies

   • Comparative pharmacology of stimulants

2. Medical examination:

   • Local anesthetic mechanisms

   • Vasoconstriction studies

3. Analüütiline keemia:

   • Reference standard for drug analysis

   • Forensic investigation

Uuringute eelised:
✅ Naturally occurring compound
✅Less addiction potential than cocaine
✅Good stability in solution
✅Suitable for in vitro receptor studies

Riskid ja piirangud:
❌ Võimalikud kõrvaltoimed:

• Tachycardia

• Hüpertensioon

• CNS stimulation
  ❌Limited pharmacokinetic data available
  ❌Potential for abuse

Annustamisprotokoll (uuringuteks):

Ohutusmeetmed:

• Wear appropriate PPE (gloves, lab coat)

• Work under a fume hood

• Avoid contact with skin and eyes

• Do not combine with MAO inhibitors

Korduma kippuvad küsimused:

1. Is Tropacocaine legal in the Netherlands?
   It may fall under the Opium Act as a cocaine-related substance.

2. How is it different from cocaine?
   Less euphoric effect, shorter duration of action.

3. Can it be used as a local anesthetic?
   For research purposes only, not for medical use.

4. Is it detectable on drug tests?
   It may cross-react with cocaine tests.

Kvaliteedikontroll ja analüütilised andmed:

Spetsifikatsioonid:

• Puhtus: ≥98% (HPLC)

• Heavy metals: <1 ppm

• Loss on drying: <0.5%

• Jäänud lahustid: <0,1%

Stabiilsusandmed:

• Shelf life: 36 months at 15-25°C

• Valgustundlikkus: Mõõdukas

• Niiskustundlikkus: kõrge

Järeldus:
Tropacocaine HCl is a valuable research substance for pharmacological and analytical studies, but requires responsible use.

⚠ For research purposes only – not for human use

Säilitamisnõuanded:

• Õhukindel pakend

• Hoida pimedas kohas

• Kuivatage temperatuuril <25°C

Eetilised kaalutlused:

• For use by qualified personnel only

• Loomkatsed vajavad eetilist heakskiitu

• Document all experiments accurately