{"id":23624,"date":"2025-04-13T17:40:07","date_gmt":"2025-04-13T17:40:07","guid":{"rendered":"https:\/\/researchchemicalstore.eu\/?post_type=product&p=23624"},"modified":"2025-10-22T15:07:41","modified_gmt":"2025-10-22T15:07:41","slug":"4-aco-20-mg-graanulitega","status":"publish","type":"product","link":"https:\/\/researchchemicalstore.eu\/et\/product\/4-aco-20-mg-graanulitega\/","title":{"rendered":"4-AcO-MET 20 mg graanulid"},"content":{"rendered":"

4-AcO-MET 20 MG graanulid \u2013 tr\u00fcptamiinide perekonna uurimisaine<\/span><\/span><\/strong><\/h1>\n

Toote nimi:<\/span><\/span><\/strong> 4-AcO-MET (4-atsetoks\u00fc-N-et\u00fc\u00fcl-N-met\u00fc\u00fcltr\u00fcptamiin) <\/span><\/span>
\nVorm:<\/span><\/span><\/strong> Pressitud pelletid, iga\u00fcks 20 mg <\/span><\/span>
\nKeemiline klass:<\/span><\/span><\/strong> Ps\u00fchhedeelne tr\u00fcptamiin <\/span><\/span>
\nMolekulaarne valem:<\/span><\/span><\/strong> C15H22N2O2 <\/span><\/span>
\nMolekulaarmass:<\/span><\/span><\/strong> 262,35 g\/mol <\/span><\/span>
\nPuhtus:<\/span><\/span><\/strong> \u226598% (kontrollitud HPLC ja NMR abil) <\/span><\/span>
\nKasutusalad:<\/span><\/span><\/strong> Ainult anal\u00fc\u00fctiliseks uurimist\u00f6\u00f6ks ja laborikasutuseks<\/span><\/span><\/p>\n

\n

Kirjeldus<\/span><\/span><\/strong><\/h2>\n

4-AcO-MET on pools\u00fcnteetiline tr\u00fcptamiin, mis on struktuurilt seotud nii psilotsiini kui ka 4-AcO-DMT-ga. Seda peetakse sageli MET-i (N-et\u00fc\u00fcl-N-met\u00fc\u00fcltr\u00fcptamiini) eelravimiks, mis on serotonergilise toimega aine. Uurimiskeskkonnas on 4-AcO-MET tuntud oma huvitavate farmakoloogiliste omaduste ja suhteliselt kergete, kuid eksperimentaalsetes mudelites m\u00e4rkimisv\u00e4\u00e4rsete visuaalsete ja kognitiivsete m\u00f5jude poolest.<\/span><\/span><\/p>\n

See <\/span><\/span>20 MG pelletit<\/span><\/span><\/strong> pakkuda laboritele standardiseeritud ja t\u00e4pset doseerimist, kus anal\u00fc\u00fcsitakse selle aine stabiilsust, interaktsiooni serotoniini retseptoritega v\u00f5i struktuurilist v\u00f5rdlust sarnaste tr\u00fcptamiinidega.<\/span><\/span><\/p>\n

\n

Rakendused teadusuuringutes<\/span><\/span><\/strong><\/h2>\n

\ud83d\udd2cRetseptori sidumise uuringud (eriti 5-HT2A, 5-HT1A) <\/span><\/span>
\n\ud83d\udd2cV\u00f5rdlev tr\u00fcptamiiniuuring: struktuurilised ja farmakoloogilised seosed <\/span><\/span>
\n\ud83d\udd2cNeurobioloogiliste protsesside visualiseerimine loommudelites <\/span><\/span>
\n\ud83d\udd2cEelravimi anal\u00fc\u00fcs ja metabolism (4-AcO-MET-ist MET-iks) <\/span><\/span>
\n\ud83d\udd2cLC-MS ja GC-MS v\u00f5rdlusstandard anal\u00fc\u00fctiliste laborite jaoks<\/span><\/span><\/p>\n

\n

Teadlaste eelised<\/span><\/span><\/strong><\/h2>\n

\u2705 Standardiseeritud graanulite doseerimine<\/span><\/span><\/strong> \u2013 Minimeerib kaalumisvigu mikrodoseerimiskatsetes <\/span><\/span>
\n\u2705 Kerged ja kontrollitavad farmakoloogilised omadused <\/span><\/span><\/strong>
\n\u2705 Huvitav eelravimi struktuur<\/span><\/span><\/strong> \u2013 Ainevahetuse ja ens\u00fcmaatilise konversiooni uurimine <\/span><\/span>
\n\u2705 K\u00f5rge puhtusaste ja stabiilsus<\/span><\/span><\/strong> \u2013 Ideaalne tulemuste replikatsiooniks<\/span><\/span><\/p>\n

\n

Puudused ja v\u00f5imalikud piirangud<\/span><\/span><\/strong><\/h2>\n

\u26a0\ufe0f Valgustundlik<\/span><\/span><\/strong> \u2013 Tuleb hoida pimedas <\/span><\/span>
\n\u26a0\ufe0f Piiratud pikaajalised andmed<\/span><\/span><\/strong> \u2013 Piiratud kliiniline kirjandus toksikoloogiliste omaduste kohta <\/span><\/span>
\n\u26a0\ufe0f Potentsiaalselt ettearvamatud m\u00f5jud loommudelites suuremate annuste korral <\/span><\/span><\/strong>
\n\u26a0\ufe0f Ei sobi kasutamiseks v\u00e4ljaspool kontrollitud uurimiskeskkonda<\/span><\/span><\/strong><\/p>\n

\n

Soovitatav laborikasutus<\/span><\/span><\/strong><\/h2>\n
    \n
  • Algannus in vitro testimiseks:<\/span><\/span><\/strong> 1\u20135 mg lahustatuna etanoolis v\u00f5i vesilahuse puhvris<\/span><\/span><\/li>\n
  • Sidumiskatsete jaoks:<\/span><\/span><\/strong> 10\u201320 \u00b5M kontsentratsioon rakukultuuri s\u00f6\u00f6tmes<\/span><\/span><\/li>\n
  • Lahustuvus:<\/span><\/span><\/strong> Hea etanoolis, m\u00f5\u00f5dukas vees<\/span><\/span><\/li>\n
  • S\u00e4ilitamine:<\/span><\/span><\/strong> Hoida kuivas, \u00f5hukindlas anumas ja jahedas (eelistatavalt alla 8 \u00b0C).<\/span><\/span><\/li>\n<\/ul>\n
    \n

    Laboriaruanne \u2013 partii andmed<\/span><\/span><\/strong><\/h2>\n\n\n\n\n\n\n\n\n\n
    Parameeter<\/span><\/span><\/th>\nSpetsifikatsioon<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
    Partii number<\/span><\/span><\/strong><\/td>\n4ACOMET-0725<\/span><\/span><\/td>\n<\/tr>\n
    Puhtus (HPLC)<\/span><\/span><\/strong><\/td>\n98.7%<\/span><\/span><\/td>\n<\/tr>\n
    Identifitseerimine<\/span><\/span><\/strong><\/td>\nKinnitatud NMR, MS ja FTIR abil<\/span><\/span><\/td>\n<\/tr>\n
    V\u00e4limus<\/span><\/span><\/strong><\/td>\nHelepruun\/valge pulber, pressitud graanuliteks<\/span><\/span><\/td>\n<\/tr>\n
    Sulamistemperatuur<\/span><\/span><\/strong><\/td>\n192\u2013195 \u00b0C<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
    \n

    Korduma kippuvad k\u00fcsimused (KKK)<\/span><\/span><\/strong><\/h2>\n

    \u2753 Kas 4-AcO-MET on Hollandis v\u00f5i Belgias legaalne?<\/span><\/span><\/em><\/h3>\n

    \u27a1\ufe0fStaatus on <\/span><\/span>hall ala<\/span><\/span><\/strong> . Ei ole oopiumiseadusega reguleeritud, kuid inimtoiduks keelatud. Lubatud ainult volitatud uuringuteks.<\/span><\/span><\/p>\n

    \u2753 Mis vahe on 4-AcO-MET-il ja 4-AcO-DMT-l?<\/span><\/span><\/em><\/h3>\n

    \u27a1\ufe0f4-AcO-MET sisaldab dimet\u00fc\u00fclr\u00fchma asemel N-et\u00fc\u00fclr\u00fchma. See v\u00f5ib viia veidi erinevate farmakoloogiliste efektideni, \u00fcldiselt leebema visuaalse intensiivsusega.<\/span><\/span><\/p>\n

    \u2753 Kuidas ma peaksin laboris graanulitega \u00fcmber k\u00e4ima?<\/span><\/span><\/em><\/h3>\n

    \u27a1\ufe0fKasutage kindaid ja milligrammi t\u00e4psusega kaalusid. Materjali lahustamisel v\u00f5i k\u00e4sitsemisel kandke laborikitlit ja t\u00f6\u00f6tage t\u00f5mbekappi all.<\/span><\/span><\/p>\n

    \u2753 Kas 4-AcO-MET-i saab pikka aega s\u00e4ilitada?<\/span><\/span><\/em><\/h3>\n

    \u27a1\ufe0fJah, kui seda hoitakse \u00f5hukindlalt ja jahedas. Optimaalse stabiilsuse tagamiseks hoida pimedas purgis temperatuuril alla 8 \u00b0C.<\/span><\/span><\/p>\n

    \u2753 Kas 4-AcO-MET muundub organismis MET-iks?<\/span><\/span><\/em><\/h3>\n

    \u27a1\ufe0fLoommudelites on n\u00e4idatud, et 4-AcO-MET muundatakse h\u00fcdrol\u00fc\u00fcsi teel MET-iks, muutes selle eelravimiks. See muudab selle ainevahetusuuringute seisukohalt huvitavaks.<\/span><\/span><\/p>\n

    \n

    Hoiatus<\/span><\/span><\/strong><\/h2>\n

    \u26a0\ufe0f Ainult kvalifitseeritud teadlastele akrediteeritud laborites kasutamiseks. Mitte tarbimiseks, diagnostikaks, terapeutiliseks kasutamiseks ega koduseks kasutamiseks.<\/span><\/span><\/strong><\/p>","protected":false},"excerpt":{"rendered":"

    4-AcO-MET 20 MG Pellets \u2013 Research Substance from the Tryptamine Family Product Name: 4-AcO-MET (4-Acetoxy-N-ethyl-N-methyltryptamine) Form: Pressed pellets, 20 mg<\/p>","protected":false},"featured_media":28680,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[503,502,324,381],"product_tag":[326],"class_list":{"0":"post-23624","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-4-aco-met","7":"product_cat-4-aco-met-pellets","8":"product_cat-pellets-for-pellet","9":"product_cat-tryptamines","10":"product_tag-nl","12":"first","13":"instock","14":"taxable","15":"shipping-taxable","16":"purchasable","17":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/researchchemicalstore.eu\/et\/wp-json\/wp\/v2\/product\/23624","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/researchchemicalstore.eu\/et\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/researchchemicalstore.eu\/et\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/et\/wp-json\/wp\/v2\/comments?post=23624"}],"version-history":[{"count":5,"href":"https:\/\/researchchemicalstore.eu\/et\/wp-json\/wp\/v2\/product\/23624\/revisions"}],"predecessor-version":[{"id":28060,"href":"https:\/\/researchchemicalstore.eu\/et\/wp-json\/wp\/v2\/product\/23624\/revisions\/28060"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/et\/wp-json\/wp\/v2\/media\/28680"}],"wp:attachment":[{"href":"https:\/\/researchchemicalstore.eu\/et\/wp-json\/wp\/v2\/media?parent=23624"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/et\/wp-json\/wp\/v2\/product_brand?post=23624"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/et\/wp-json\/wp\/v2\/product_cat?post=23624"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/et\/wp-json\/wp\/v2\/product_tag?post=23624"}],"curies":[{"name":"t\u00f6\u00f6leht","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}