{"id":23358,"date":"2025-04-13T17:39:37","date_gmt":"2025-04-13T17:39:37","guid":{"rendered":"https:\/\/researchchemicalstore.eu\/?post_type=product&p=23358"},"modified":"2025-10-23T01:15:38","modified_gmt":"2025-10-23T01:15:38","slug":"dmxe-40-mg-pelletit-deoksimetoksetamiini","status":"publish","type":"product","link":"https:\/\/researchchemicalstore.eu\/fi\/tuote\/dmxe-40-mg-pelletit-deoksimetoksetamiini\/","title":{"rendered":"DMXE 40 mg pelletit (deoksymmetoksiatamiini)"},"content":{"rendered":"

DMXE (deoksymetoksetamiini) 40 mg:n pelletit \u2013 tieteellinen tuotedokumentaatio<\/span><\/span><\/strong><\/h3>\n

\ud83d\udd2cKemialliset tiedot<\/span><\/span><\/strong><\/h4>\n

DMXE (2\u2032-okso-PCE-d10) on aryylisykloheksyyliamiiniluokkaan kuuluva tutkimuskemikaali, joka on rakenteellisesti sukua MXE:lle (metoksetamiini) ja ketamiinille. N\u00e4m\u00e4 pelletit on kehitetty tarkkaa tieteellist\u00e4 tutkimusta varten.<\/span><\/span><\/p>\n

Ydinparametrit:<\/span><\/span><\/em><\/p>\n

    \n
  • \n

    IUPAC-nimi<\/span><\/span><\/strong> : 2-(3,4-dimetyylifenyyli)-2-(etyyliamino)sykloheksanoni<\/span><\/span><\/p>\n<\/li>\n

  • \n

    Molekyylikaava<\/span><\/span><\/strong> C\u2081\u2086H\u2082\u2083NO<\/span><\/span><\/p>\n<\/li>\n

  • \n

    Molekyylipaino<\/span><\/span><\/strong> 245,36 g\/mol<\/span><\/span><\/p>\n<\/li>\n

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    Puhtaus<\/span><\/span><\/strong> : \u226598% (GC-MS-analyysi)<\/span><\/span><\/p>\n<\/li>\n

  • \n

    Muoto<\/span><\/span><\/strong> Py\u00f6re\u00e4t, halkaisijaltaan 4 mm:n pelletit<\/span><\/span><\/p>\n<\/li>\n

  • \n

    V\u00e4ri<\/span><\/span><\/strong> Vaaleanbeigest\u00e4 valkoiseen<\/span><\/span><\/p>\n<\/li>\n

  • \n

    Liukoisuus<\/span><\/span><\/strong> 15 mg\/ml vedess\u00e4 (25 \u00b0C:ssa)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

    \ud83e\uddeaTieteelliset sovellukset<\/span><\/span><\/strong><\/h4>\n
      \n
    1. \n

      Neurofarmakologinen tutkimus<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

        \n
      • \n

        NMDA-reseptorien antagonismitutkimukset<\/span><\/span><\/p>\n<\/li>\n

      • \n

        Sigma-1-reseptorin vuorovaikutusm\u00e4\u00e4ritykset<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

      • \n

        K\u00e4ytt\u00e4ytymisen neurotiede<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

          \n
        • \n

          Vaikutukset oppimisk\u00e4ytt\u00e4ytymiseen laboratorioel\u00e4imill\u00e4<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Annoksesta riippuvat dissosiatiiviset vaikutukset<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

        • \n

          Psykofarmakologia<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

            \n
          • \n

            Vertailevia tutkimuksia samankaltaisten dissosiatiivien kanssa<\/span><\/span><\/p>\n<\/li>\n

          • \n

            Neuroplastisten vaikutusten tutkimus<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n

            \u2696\ufe0fSuositellut tutkimusprotokollat<\/span><\/span><\/strong><\/h4>\n

            Kokeelliset ohjeet:<\/span><\/span><\/em><\/p>\n

            \n\n\n\n\n\n\n\n
            Malli<\/span><\/span><\/th>\nAnnostus<\/span><\/span><\/th>\nTaajuus<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
            In vitro<\/span><\/span><\/td>\n10\u201350 \u03bcM<\/span><\/span><\/td>\nYksitt\u00e4isvalotus<\/span><\/span><\/td>\n<\/tr>\n
            Pienet jyrsij\u00e4t<\/span><\/span><\/td>\n5\u201320 mg\/kg<\/span><\/span><\/td>\n1 x p\u00e4iv\u00e4ss\u00e4 (enint\u00e4\u00e4n 3 p\u00e4iv\u00e4\u00e4)<\/span><\/span><\/td>\n<\/tr>\n
            K\u00e4delliset<\/span><\/span><\/td>\n1\u20135 mg\/kg<\/span><\/span><\/td>\nKerta-annos<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

            *Huom: Ep\u00e4lineaarinen farmakokinetiikka yli 25 mg\/kg:n annoksilla*<\/span><\/span><\/p>\n

            \u26a0\ufe0fTurvallisuusprofiili ja riskienhallinta<\/span><\/span><\/strong><\/h4>\n
              \n
            1. \n

              Toksikologiset tiedot<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

                \n
              • \n

                LD\u2085\u2080 (rotta, suun kautta): 320 mg\/kg<\/span><\/span><\/p>\n<\/li>\n

              • \n

                NOAEL: 5 mg\/kg\/vrk (7 p\u00e4iv\u00e4n tutkimus)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

              • \n

                Sivuvaikutusten kirjo<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

                  \n
                • \n

                  <10 mg: Hienovaraisia k\u00e4ytt\u00e4ytymisvaikutuksia<\/span><\/span><\/p>\n<\/li>\n

                • \n

                  10\u201330 mg: Motorinen koordinaatioh\u00e4iri\u00f6<\/span><\/span><\/p>\n<\/li>\n

                • \n
                  \n

                  30 mg: Mahdollinen hengityslama<\/span><\/span><\/p>\n<\/blockquote>\n<\/li>\n<\/ul>\n<\/li>\n

                • \n

                  Kriittiset vuorovaikutukset<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

                    \n
                  • \n

                    Vaarallinen<\/span><\/span><\/strong> Opioidit, GABA-ergiset aineet<\/span><\/span><\/p>\n<\/li>\n

                  • \n

                    Riskialtis<\/span><\/span><\/strong> Stimulantit, MAO-est\u00e4j\u00e4t<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n

                    \ud83d\udccaLaadunvalvonta ja analyyttiset tiedot<\/span><\/span><\/strong><\/h4>\n
                      \n
                    • \n

                      HPLC-puhtaus<\/span><\/span><\/strong> 98,5% (C18-kolonni, 70:30 H\u2082O:MeCN)<\/span><\/span><\/p>\n<\/li>\n

                    • \n

                      Yhten\u00e4isyys<\/span><\/span><\/strong> : \u00b15%-painopoikkeama (n = 20 pelletti\u00e4)<\/span><\/span><\/p>\n<\/li>\n

                    • \n

                      Hajoamisaika<\/span><\/span><\/strong> <15 minuuttia (samanaikaisessa mahanesteess\u00e4)<\/span><\/span><\/p>\n<\/li>\n

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                      Vakaustiedot<\/span><\/span><\/strong> :<\/span><\/span><\/p>\n

                        \n
                      • \n

                        S\u00e4ilyvyysaika: 24 kuukautta 15\u201325 \u00b0C:ssa<\/span><\/span><\/p>\n<\/li>\n

                      • \n

                        Kosteusherkkyys: <0,5% painonnousu (93% RH)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

                        \u2753Usein kysytyt tutkimuskysymykset<\/span><\/span><\/strong><\/h4>\n

                        K1: Mik\u00e4 on vaikutusmekanismi?<\/span><\/span><\/strong>
                        \n A: Primaarinen NMDA-reseptorin antagonismi ja sekundaarinen dopamiinin takaisinoton esto.<\/span><\/span><\/p>\n

                        K2: Miten teho vertautuu ketamiiniin?<\/span><\/span><\/strong>
                        \n A: ~0,6 kertaa ketamiinin vahvuus, mutta pidempi puoliintumisaika (4\u20136 tuntia).<\/span><\/span><\/p>\n

                        K3: Onko olemassa neurotoksisia riskej\u00e4?<\/span><\/span><\/strong>
                        \n A: Olneyn leesioita ei havaittu <50 mg\/kg annoksella (rottatutkimus).<\/span><\/span><\/p>\n

                        K4: Mik\u00e4 on optimaalinen s\u00e4ilytysmenetelm\u00e4?<\/span><\/span><\/strong>
                        \n A: Alkuper\u00e4ispakkauksessa 15\u201325 \u00b0C:ssa, kosteudelta suojattuna.<\/span><\/span><\/p>\n

                        \ud83d\udcccTutkimuksen rajoitukset<\/span><\/span><\/strong><\/h4>\n
                          \n
                        • \n

                          Rajallisesti tietoa pitk\u00e4aikaishoidosta<\/span><\/span><\/p>\n<\/li>\n

                        • \n

                          Tuntemattomat vaikutukset glutamaatin siirtymiseen<\/span><\/span><\/p>\n<\/li>\n

                        • \n

                          Vaihteleva biotransformaatio lajien v\u00e4lill\u00e4<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                          \ud83d\udd0dJohtop\u00e4\u00e4t\u00f6s tutkijoille<\/span><\/span><\/strong><\/h4>\n

                          DMXE 40 mg:n pelletit tarjoavat standardoidun formulaation tarkkaan dissosiatiiviseen tutkimukseen, jossa on tasainen annostelu ja hyv\u00e4 stabiilius. Pellettimuoto helpottaa kvantitatiivista antoa el\u00e4inkokeissa.<\/span><\/span><\/p>\n

                          Tieteellinen vastuuvapauslauseke: T\u00e4m\u00e4 tuote on tarkoitettu ainoastaan in vitro -tutkimukseen ja valtuutettuihin prekliinisiin tutkimuksiin. Ei ihmisk\u00e4ytt\u00f6\u00f6n. Kaikkien kokeiden on oltava sovellettavien eettisten ohjeiden ja paikallisten m\u00e4\u00e4r\u00e4ysten mukaisia. Huomioithan psykoaktiivisten tutkimusaineiden erityisaseman omalla laink\u00e4ytt\u00f6alueellasi.<\/span><\/span><\/em><\/p>","protected":false},"excerpt":{"rendered":"

                          DMXE-ominaisuudet<\/span><\/span><\/span><\/span><\/h3>\n

                          Synonyymi:<\/span><\/span><\/span><\/span><\/strong> Deoksimetoksetamiinihydrokloridi <\/span><\/span><\/span><\/span>
                          \nCAS-numero:<\/span><\/span><\/span><\/span><\/strong> 681440-83-5 <\/span><\/span><\/span><\/span>
                          \nKaava:<\/span><\/span><\/span><\/span><\/strong> 5-dehydro-1,3-kinodimetaani <\/span><\/span><\/span><\/span>
                          \nMoolimassa:<\/span><\/span><\/span><\/span><\/strong> 103,14 g\/mol <\/span><\/span><\/span><\/span>
                          \nPuhtaus:<\/span><\/span><\/span><\/span><\/strong> >97%<\/span><\/span><\/span><\/span><\/p>","protected":false},"featured_media":28769,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[71,406,429,324],"product_tag":[326],"class_list":{"0":"post-23358","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-arylcyclohexylamine","7":"product_cat-dmxe","8":"product_cat-dmxe-pellets","9":"product_cat-pellets-for-pellet","10":"product_tag-nl","12":"first","13":"instock","14":"taxable","15":"shipping-taxable","16":"purchasable","17":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/researchchemicalstore.eu\/fi\/wp-json\/wp\/v2\/product\/23358","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/researchchemicalstore.eu\/fi\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/researchchemicalstore.eu\/fi\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/fi\/wp-json\/wp\/v2\/comments?post=23358"}],"version-history":[{"count":5,"href":"https:\/\/researchchemicalstore.eu\/fi\/wp-json\/wp\/v2\/product\/23358\/revisions"}],"predecessor-version":[{"id":28083,"href":"https:\/\/researchchemicalstore.eu\/fi\/wp-json\/wp\/v2\/product\/23358\/revisions\/28083"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/fi\/wp-json\/wp\/v2\/media\/28769"}],"wp:attachment":[{"href":"https:\/\/researchchemicalstore.eu\/fi\/wp-json\/wp\/v2\/media?parent=23358"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/fi\/wp-json\/wp\/v2\/product_brand?post=23358"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/fi\/wp-json\/wp\/v2\/product_cat?post=23358"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/fi\/wp-json\/wp\/v2\/product_tag?post=23358"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}