{"id":23655,"date":"2025-04-13T17:40:11","date_gmt":"2025-04-13T17:40:11","guid":{"rendered":"https:\/\/researchchemicalstore.eu\/?post_type=product&p=23655"},"modified":"2025-10-22T14:57:47","modified_gmt":"2025-10-22T14:57:47","slug":"idra-21-pelete-od-10-mg","status":"publish","type":"product","link":"https:\/\/researchchemicalstore.eu\/hr\/product\/idra-21-pelete-od-10-mg\/","title":{"rendered":"IDRA-21 pelete od 10 mg"},"content":{"rendered":"

IDRA-21 10 MG pelete \u2013 Znanstveni opis i upute za uporabu<\/span><\/span><\/strong><\/h3>\n

Opis proizvoda<\/span><\/span><\/strong><\/h4>\n

IDRA-21 (pelete od 10 mg)<\/span><\/span><\/strong> \u00a0je potencijal\u00a0 <\/span><\/span>Potencijator AMPA receptora<\/span><\/span><\/strong> \u00a0koji pripadaju klasi\u00a0 <\/span><\/span>nootropne i neuroprotektivne istra\u017eiva\u010dke kemikalije<\/span><\/span><\/strong> . Djeluje poja\u010davanjem signalizacije inducirane glutamatom u mozgu, \u0161to mo\u017ee dovesti do pobolj\u0161ane kognitivne funkcije, neuroplasti\u010dnosti i potencijalno neurooporavka.<\/span><\/span><\/p>\n

Ove pelete su\u00a0 <\/span><\/span>visoka \u010disto\u0107a (\u226598%)<\/span><\/span><\/strong> , standardizirano dozirano i namijenjeno isklju\u010divo za\u00a0 <\/span><\/span>znanstvena istra\u017eivanja i predklini\u010dke studije<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n

\n

Upotreba i primjene<\/span><\/span><\/strong><\/h3>\n

IDRA-21 se prou\u010dava zbog mogu\u0107ih u\u010dinaka na:<\/span><\/span><\/p>\n

    \n
  1. \n

    Kognitivno pobolj\u0161anje<\/span><\/span><\/strong> \u00a0\u2013 Mo\u017ee pove\u0107ati budnost, sposobnost u\u010denja i konsolidaciju pam\u0107enja.<\/span><\/span><\/p>\n<\/li>\n

  2. \n

    Neuroprotekcija<\/span><\/span><\/strong> \u00a0\u2013 Potencijalni za\u0161titni u\u010dinak kod neurodegenerativnih bolesti (npr. Alzheimerova bolest, mo\u017edani udar).<\/span><\/span><\/p>\n<\/li>\n

  3. \n

    Neurolo\u0161ki oporavak<\/span><\/span><\/strong> \u00a0\u2013 Mo\u017ee potaknuti sinapti\u010dku plasti\u010dnost nakon ozljede mozga.<\/span><\/span><\/p>\n<\/li>\n

  4. \n

    Znanstveno istra\u017eivanje<\/span><\/span><\/strong> \u00a0\u2013 Prou\u010davanje modulacije AMPA receptora i signalizacije glutamata.<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

    \u26a0\u00a0Nije odobreno za ljudsku ili veterinarsku uporabu \u2013 Samo za in vitro i kontrolirane predklini\u010dke studije.<\/span><\/span><\/strong><\/p>\n

    \n

    Smjernice za doziranje i sigurnost<\/span><\/span><\/strong><\/h3>\n
      \n
    • \n

      Ispitivana doza (in vitro\/preklini\u010dka): <\/span><\/span><\/strong>\u00a05\u201320 mg\/kg<\/span><\/span><\/strong> \u00a0(ovisno o modelu).<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Otopina peleta:<\/span><\/span><\/strong> \u00a0Mo\u017ee se otopiti u\u00a0 <\/span><\/span>destilirana voda ili DMSO<\/span><\/span><\/strong> \u00a0za eksperimente.<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Administracija:<\/span><\/span><\/strong> \u00a0Oralno (\u017eivotinjski modeli) ili izravno u stani\u010dnim kulturama.<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Frekvencija:<\/span><\/span><\/strong> \u00a0Jedna doza za akutni u\u010dinak; dugotrajne studije zahtijevaju pa\u017eljivo pra\u0107enje.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

      \ud83d\udea8\u00a0Napomena:<\/span><\/span><\/strong><\/p>\n

        \n
      • \n

        Nema ljudske primjene<\/span><\/span><\/strong> \u00a0\u2013 Nema podataka o sigurnosti za ljudsku upotrebu.<\/span><\/span><\/p>\n<\/li>\n

      • \n

        Visoke doze mogu uzrokovati neuroekscitotoksi\u010dnost.<\/span><\/span><\/strong><\/p>\n<\/li>\n

      • \n

        Izbjegavajte kombinaciju s drugim modulatorima glutamata.<\/span><\/span><\/strong><\/p>\n<\/li>\n<\/ul>\n

        \n

        Nedostaci i rizici<\/span><\/span><\/strong><\/h3>\n
          \n
        • \n

          Prekomjerna stimulacija neurona<\/span><\/span><\/strong> \u00a0(rizik od ekscitotoksi\u010dnosti u slu\u010daju predoziranja).<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Mogu\u0107a anksioznost ili uznemirenost<\/span><\/span><\/strong> \u00a0kod osjetljivih modela.<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Ograni\u010deni dugoro\u010dni podaci<\/span><\/span><\/strong> \u00a0o toleranciji i nuspojavama.<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Nije prikladno za kroni\u010dnu upotrebu<\/span><\/span><\/strong> \u00a0bez opse\u017enih studija toksi\u010dnosti.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

          \n

          \u010cesto postavljana pitanja (FAQs)<\/span><\/span><\/strong><\/h3>\n

          1. Je li IDRA-21 legalan u Nizozemskoj?<\/span><\/span><\/strong><\/h4>\n

          Da, ali samo za\u00a0 <\/span><\/span>znanstveno istra\u017eivanje<\/span><\/span><\/strong> . Ne potpada pod Zakon o opijumu, ali nije ni odobren kao lijek.<\/span><\/span><\/p>\n

          2. Kako to\u010dno IDRA-21 djeluje?<\/span><\/span><\/strong><\/h4>\n

          To\u00a0 <\/span><\/span>poja\u010dava odgovor AMPA receptora<\/span><\/span><\/strong> , \u0161to \u010dini signalizaciju glutamata duljom i intenzivnijom. To mo\u017ee dovesti do pobolj\u0161ane sinapti\u010dke komunikacije.<\/span><\/span><\/p>\n

          3. Mo\u017ee li se IDRA-21 usporediti s drugim nootropicima?<\/span><\/span><\/strong><\/h4>\n

          Ima jedinstven mehanizam djelovanja, ali\u00a0 <\/span><\/span>sli\u010dne mete kao racetami ili ampakini<\/span><\/span><\/strong> \u00a0(npr. Sunifiram).<\/span><\/span><\/p>\n

          4. Postoje li neke poznate interakcije?<\/span><\/span><\/strong><\/h4>\n
            \n
          • \n

            NMDA antagonisti<\/span><\/span><\/strong> \u00a0(npr. memantin) \u2013 Potencijalno \u0161tetni u\u010dinci.<\/span><\/span><\/p>\n<\/li>\n

          • \n

            GABAergi\u010dni agensi<\/span><\/span><\/strong> \u00a0(npr. benzodiazepini) \u2013 Mogu smanjiti anksioliti\u010dke u\u010dinke.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

            \n

            Laboratorijsko izvje\u0161\u0107e i kontrola kvalitete<\/span><\/span><\/strong><\/h3>\n
              \n
            • \n

              HPLC analiza: <\/span><\/span><\/strong>\u00a0\u010disto\u0107a \u226598%<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Nema detektabilnih te\u0161kih metala ili ostataka otapala<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Homogena formulacija peleta<\/span><\/span><\/strong> \u00a0za dosljedno doziranje.<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Certifikacija serije<\/span><\/span><\/strong> \u00a0dostupni istra\u017eiva\u010dkim institucijama.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

              \n

              Preporu\u010deni istra\u017eiva\u010dki scenariji<\/span><\/span><\/strong><\/h3>\n
                \n
              1. \n

                Kognitivne studije<\/span><\/span><\/strong> \u00a0\u2013 Utjecaji na pam\u0107enje i u\u010denje kod \u017eivotinjskih modela.<\/span><\/span><\/p>\n<\/li>\n

              2. \n

                Neuroprotektivna istra\u017eivanja<\/span><\/span><\/strong> \u00a0\u2013 Potencijalna uloga u ishemijskoj ozljedi (modeli mo\u017edanog udara).<\/span><\/span><\/p>\n<\/li>\n

              3. \n

                Elektrofiziologija<\/span><\/span><\/strong> \u00a0\u2013 Mjerenja odgovora AMPA receptora u neuronskim kulturama.<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

                \ud83d\udd2c\u00a0Samo za kontroliranu laboratorijsku uporabu \u2013 Nije za rekreativnu uporabu!<\/span><\/span><\/strong><\/p>\n

                ","protected":false},"excerpt":{"rendered":"

                Svojstva IDRA-21 peleta<\/span><\/span><\/h3>\n

                Sinonim<\/span><\/span><\/strong> 7-kloro-3-metil-3,4-dihidro-2H-1,2,4-benzotiadiazin 1,1-dioksid <\/span><\/span>
                \nCAS <\/span><\/span><\/strong> Broj<\/span><\/span><\/strong> : 22503-72-6 <\/span><\/span>
                \nFormula<\/span><\/span><\/strong> C8H9ClN2O2S <\/span><\/span>
                \nMolarna masa<\/span><\/span><\/strong> : 232,6 g\/mol <\/span><\/span>
                \n\u010cisto\u0107a<\/span><\/span><\/strong> : >97%<\/span><\/span><\/p>","protected":false},"featured_media":28802,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[548,549,330,324],"product_tag":[326],"class_list":["post-23655","product","type-product","status-publish","has-post-thumbnail","product_cat-idra-21","product_cat-idra-21-pellets","product_cat-nootropics","product_cat-pellets-for-pellet","product_tag-nl","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/researchchemicalstore.eu\/hr\/wp-json\/wp\/v2\/product\/23655","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/researchchemicalstore.eu\/hr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/researchchemicalstore.eu\/hr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/hr\/wp-json\/wp\/v2\/comments?post=23655"}],"version-history":[{"count":5,"href":"https:\/\/researchchemicalstore.eu\/hr\/wp-json\/wp\/v2\/product\/23655\/revisions"}],"predecessor-version":[{"id":28058,"href":"https:\/\/researchchemicalstore.eu\/hr\/wp-json\/wp\/v2\/product\/23655\/revisions\/28058"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/hr\/wp-json\/wp\/v2\/media\/28802"}],"wp:attachment":[{"href":"https:\/\/researchchemicalstore.eu\/hr\/wp-json\/wp\/v2\/media?parent=23655"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/hr\/wp-json\/wp\/v2\/product_brand?post=23655"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/hr\/wp-json\/wp\/v2\/product_cat?post=23655"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/hr\/wp-json\/wp\/v2\/product_tag?post=23655"}],"curies":[{"name":"radni list","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}