{"id":23497,"date":"2025-04-13T17:39:53","date_gmt":"2025-04-13T17:39:53","guid":{"rendered":"https:\/\/researchchemicalstore.eu\/?post_type=product&p=23497"},"modified":"2025-10-22T16:53:50","modified_gmt":"2025-10-22T16:53:50","slug":"5-meo-dmt-fritt","status":"publish","type":"product","link":"https:\/\/researchchemicalstore.eu\/is\/vara\/5-meo-dmt-fritt\/","title":{"rendered":"5-MeO-DMT fr\u00edtt basa"},"content":{"rendered":"

5-MeO-DMT Freebase \u2013 V\u00edsindaleg v\u00f6ruuppl\u00fdsingar<\/span><\/span><\/strong><\/h3>\n

Almenn l\u00fdsing<\/span><\/span><\/strong><\/h4>\n

5-MeO-DMT (5-Metox\u00fd-N,N-d\u00edmet\u00fdltryptam\u00edn) fr\u00edbasi er n\u00e1tt\u00farulegt tryptam\u00edn me\u00f0 \u00f6fluga ge\u00f0virka eiginleika, sem finnst \u00ed \u00fdmsum pl\u00f6ntu- og d\u00fdraseytum. \u00cd fr\u00edbasaformi b\u00fd\u00f0ur \u00fea\u00f0 upp \u00e1 yfirbur\u00f0a rokgjarnleika fyrir \u00e1kve\u00f0nar ranns\u00f3knara\u00f0fer\u00f0ir, sem gerir \u00fea\u00f0 ver\u00f0m\u00e6tt fyrir lyfjafr\u00e6\u00f0ilegar og taugav\u00edsindalegar ranns\u00f3knir.<\/span><\/span><\/p>\n

\n

T\u00e6knilegar uppl\u00fdsingar<\/span><\/span><\/strong><\/h3>\n
\n\n\n\n\n\n\n\n\n\n\n\n
F\u00e6ribreyta<\/span><\/span><\/strong><\/th>\nUppl\u00fdsingar<\/span><\/span><\/strong><\/th>\n<\/tr>\n<\/thead>\n
Efnaform\u00fala<\/span><\/span><\/td>\nC\u2081\u2083H\u2081\u2088N\u2082O<\/span><\/span><\/td>\n<\/tr>\n
M\u00f3l\u00feungi<\/span><\/span><\/td>\n218,29 g\/m\u00f3l<\/span><\/span><\/td>\n<\/tr>\n
Hreinleiki<\/span><\/span><\/td>\n\u226598% (HPLC-UV greint)<\/span><\/span><\/td>\n<\/tr>\n
Ey\u00f0ubla\u00f0<\/span><\/span><\/td>\nKristalla\u00f0\/hv\u00edtt duft<\/span><\/span><\/td>\n<\/tr>\n
Leysni<\/span><\/span><\/td>\nLeysanlegt \u00ed l\u00edfr\u00e6num leysum (etan\u00f3li, metan\u00f3li, DMSO), takmarka\u00f0 \u00ed vatni<\/span><\/span><\/td>\n<\/tr>\n
Br\u00e6\u00f0slumark<\/span><\/span><\/td>\n60-65\u00b0C (frj\u00e1ls basi)<\/span><\/span><\/td>\n<\/tr>\n
St\u00f6\u00f0ugleiki<\/span><\/span><\/td>\nLj\u00f3s- og s\u00farefnisn\u00e6mt; geymi\u00f0 undir \u00f3virku gasi<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
\n

V\u00edsindaleg notkun<\/span><\/span><\/strong><\/h3>\n

1. Taugalyfjafr\u00e6\u00f0ilegar ranns\u00f3knir<\/span><\/span><\/strong><\/h4>\n
    \n
  • \n

    Ser\u00f3t\u00f3nerg \u00e1hrif:<\/span><\/span><\/strong> \u00a0\u00d6flugur 5-HT\u2081\u2090\/\u2082\u2090 \u00f6rvi, vi\u00f0eigandi fyrir ranns\u00f3knir \u00e1 me\u00f0vitundarst\u00fdringu.<\/span><\/span><\/p>\n<\/li>\n

  • \n

    EEG\/fMRI ranns\u00f3knir:<\/span><\/span><\/strong> \u00a0Ranns\u00f3kn \u00e1 br\u00e1\u00f0um \u00e1hrifum \u00e1 bylgjumynstur heilans (t.d. gammasveiflur).<\/span><\/span><\/p>\n<\/li>\n

  • \n

    Taugam\u00f3tun:<\/span><\/span><\/strong> \u00a0M\u00f6guleg \u00e1hrif sem auka BDNF (\u00ed d\u00fdral\u00edk\u00f6num).<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

    2. Efnaskipta- og eiturefnafr\u00e6\u00f0ilegar ranns\u00f3knir<\/span><\/span><\/strong><\/h4>\n
      \n
    • \n

      MAO-h\u00e1\u00f0 efnaskipti:<\/span><\/span><\/strong> \u00a0Ranns\u00f3kn \u00e1 ni\u00f0urbrotsferlum CYP2D6 og MAO-A.<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Skammtah\u00e1\u00f0 eitur\u00e1hrif:<\/span><\/span><\/strong> \u00a0\u00c1kv\u00f6r\u00f0un \u00f6ryggismarka \u00ed frumur\u00e6ktun.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

      3. Samanbur\u00f0arlyfjafr\u00e6\u00f0i<\/span><\/span><\/strong><\/h4>\n
        \n
      • \n

        \u00cd samanbur\u00f0i vi\u00f0 DMT:<\/span><\/span><\/strong> \u00a0Meiri virkni en styttri verkunart\u00edmi (15-30 m\u00edn\u00fatur vi\u00f0 inn\u00f6ndun).<\/span><\/span><\/p>\n<\/li>\n

      • \n

        Samanbori\u00f0 vi\u00f0 psilocybin:<\/span><\/span><\/strong> \u00a0Mismunur \u00e1 s\u00e6kni vi\u00f0taka og hugl\u00e6gum \u00e1hrifum.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

        \n

        Tilraunalei\u00f0beiningar<\/span><\/span><\/strong><\/h3>\n

        R\u00e1\u00f0lag\u00f0ur styrkur (in vitro)<\/span><\/span><\/strong><\/h4>\n
        \n\n\n\n\n\n\n\n
        Ums\u00f3kn<\/span><\/span><\/th>\nStyrkleikasvi\u00f0<\/span><\/span><\/th>\nLeysiefni<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
        Vi\u00f0takabindingarpr\u00f3fanir<\/span><\/span><\/td>\n1 nM \u2013 10 \u00b5M<\/span><\/span><\/td>\nPBS\/DMSO (\u22640,1%)<\/span><\/span><\/td>\n<\/tr>\n
        Tilraunir \u00ed frumur\u00e6ktun<\/span><\/span><\/td>\n0,1 \u2013 100 \u00b5M<\/span><\/span><\/td>\nDMEM\/FBS<\/span><\/span><\/td>\n<\/tr>\n
        Gaskromatografi<\/span><\/span><\/td>\n1 mg\/ml (\u00ed metan\u00f3li)<\/span><\/span><\/td>\nMetan\u00f3l (HPLC-g\u00e6\u00f0i)<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

        \u00d6ryggisreglur<\/span><\/span><\/strong><\/h4>\n
          \n
        • \n

          Pers\u00f3nuvernd:<\/span><\/span><\/strong> \u00a0Ranns\u00f3knarstofusloppur, n\u00edtr\u00edlhanskar, \u00f6ryggisgleraugu, FFP2-gr\u00edma vi\u00f0 me\u00f0h\u00f6ndlun dufts.<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Loftr\u00e6sting:<\/span><\/span><\/strong> \u00a0Vinni\u00f0 alltaf undir dragsk\u00e1p \u00feegar hita\u00f0\/gufa\u00f0 er upp.<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Geymsla:<\/span><\/span><\/strong> \u00a0\u00cd gulbr\u00fanum hettugl\u00f6sum, undir argoni, vi\u00f0 -20\u00b0C (langt\u00edma).<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

          \n

          St\u00f6\u00f0ugleiki og geymsla<\/span><\/span><\/strong><\/h3>\n
            \n
          • \n

            Geymslu\u00feol:<\/span><\/span><\/strong><\/p>\n

              \n
            • \n

              Herbergishitastig: <24 klukkustundir \u00ed lausn.<\/span><\/span><\/p>\n<\/li>\n

            • \n

              4\u00b0C: St\u00f6\u00f0ugt \u00ed 3 daga (undir argoni).<\/span><\/span><\/p>\n<\/li>\n

            • \n

              -20\u00b0C: >6 m\u00e1nu\u00f0ir (\u00f3breytt hreinleiki).<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

            • \n

              Ni\u00f0urbrotsefni:<\/span><\/span><\/strong><\/p>\n

                \n
              • \n

                Oxun \u00ed ind\u00f3laflei\u00f0ur (athuga\u00f0 me\u00f0 TLC\/HPLC).<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

                \n

                Greiningarvottun<\/span><\/span><\/strong><\/h3>\n

                Hver lota inniheldur:<\/span><\/span><\/p>\n

                  \n
                1. \n

                  HPLC-UV litr\u00f3fsgreining<\/span><\/span><\/strong> \u00a0(\u03bb=280 nm, C18 s\u00fala)<\/span><\/span><\/p>\n<\/li>\n

                2. \n

                  Sta\u00f0festing me\u00f0 GC-MS<\/span><\/span><\/strong> \u00a0(einkennandi brot: m\/z 174, 160)<\/span><\/span><\/p>\n<\/li>\n

                3. \n

                  Greining \u00e1 leifar af leysiefni<\/span><\/span><\/strong> \u00a0(\u2264500 ppm)<\/span><\/span><\/p>\n<\/li>\n

                4. \n

                  Vatnsinnihald<\/span><\/span><\/strong> \u00a0(Karl Fischer, <1%)<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

                  \n

                  L\u00f6gleg sta\u00f0a (Holland)<\/span><\/span><\/strong><\/h3>\n
                    \n
                  • \n

                    \u00d3p\u00eduml\u00f6g:<\/span><\/span><\/strong> \u00a0Ekki beint regluger\u00f0arbundi\u00f0, en hugsanlega samkv\u00e6mt samb\u00e6rilegum l\u00f6gum.<\/span><\/span><\/p>\n<\/li>\n

                  • \n

                    L\u00f6ggj\u00f6f:<\/span><\/span><\/strong> \u00a0Leyfi er krafist fyrir v\u00edsindastofnanir (vi\u00f0auki 2, \u00f3p\u00eduml\u00f6g).<\/span><\/span><\/p>\n<\/li>\n

                  • \n

                    \u00datflutningstakmarkanir:<\/span><\/span><\/strong> \u00a0CITES skr\u00e1ning (vegna n\u00e1tt\u00farulegra uppspretta eins og\u00a0 <\/span><\/span>Incilius alvarius<\/span><\/span><\/em> ).<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                    \n

                    Algengar spurningar (FAQ)<\/span><\/span><\/strong><\/h3>\n

                    Spurning 1: Hver er munurinn \u00e1 fr\u00edbasa og f\u00famars\u00fdrusalti?<\/span><\/span><\/strong>
                    \n A: Fr\u00edbasi er rokgj\u00f6rnari (hentar vel fyrir uppgufunartilraunir) en f\u00famars\u00fdrusalt er st\u00f6\u00f0ugra \u00ed lausnum.<\/span><\/span><\/p>\n

                    Spurning 2: Hvernig er 5-MeO-DFT greint \u00ed eiturefnaskimun?<\/span><\/span><\/strong>
                    \n A: Au\u00f0kennilegt me\u00f0:<\/span><\/span><\/p>\n

                      \n
                    • \n

                      LC-MS\/MS (forveraj\u00f3n m\/z 219 \u2192 afur\u00f0aj\u00f3n m\/z 174)<\/span><\/span><\/p>\n<\/li>\n

                    • \n

                      \u00d3n\u00e6mispr\u00f3f: Krossvirkni vi\u00f0 sum DMT pr\u00f3f (\u226430%).<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                      Spurning 3: Eru einhverjar \u00feekktar lyfjahvarfafr\u00e6\u00f0ilegar milliverkanir?<\/span><\/span><\/strong>
                      \n A:\u00a0 <\/span><\/span>H\u00e6ttulegar samsetningar:<\/span><\/span><\/strong><\/p>\n

                        \n
                      • \n

                        MAO-hemlar (h\u00e6tta \u00e1 ser\u00f3t\u00f3n\u00ednheilkenni).<\/span><\/span><\/p>\n<\/li>\n

                      • \n

                        SSRI lyf (minnku\u00f0 virkni vegna samkeppni).<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                        Q4: Hvernig \u00e1 a\u00f0 farga \u00fargangi?<\/span><\/span><\/strong>
                        \n A: \u00d3virkja me\u00f0:<\/span><\/span><\/p>\n

                          \n
                        1. \n

                          \u00deynntu salts\u00fdra (0,1M) til hlutleysingar.<\/span><\/span><\/p>\n<\/li>\n

                        2. \n

                          Fr\u00e1sog me\u00f0 virku kolefni.<\/span><\/span><\/p>\n<\/li>\n

                        3. \n

                          Farga eins og\u00a0 <\/span><\/span>h\u00e6ttulegt efna\u00fargang<\/span><\/span><\/em> \u00a0(Sameinu\u00f0u \u00fej\u00f3\u00f0anna n\u00famer: 3249).<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

                          \n

                          Tilv\u00edsanir og tengili\u00f0ir<\/span><\/span><\/strong><\/h3>\n

                          Helstu \u00fatg\u00e1fur:<\/span><\/span><\/strong><\/p>\n

                            \n
                          • \n

                            Szara, S. (2007). "DMT og 5-MeO-DMT: Snemma ranns\u00f3knir \u00e1 m\u00f6nnum".<\/span><\/span><\/p>\n<\/li>\n

                          • \n

                            Uthaug o.fl. (2021). \u201cS\u00e1llyfjafr\u00e6\u00f0i 5-MeO-DMT\u201d.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                            \n

                            \u00deessi vara er eing\u00f6ngu \u00e6tlu\u00f0 til l\u00f6gm\u00e6tra v\u00edsindaranns\u00f3kna. Ekki til notkunar fyrir menn e\u00f0a d\u00fdr. Notendur ver\u00f0a a\u00f0 fara eftir \u00f6llum gildandi reglum.<\/span><\/span><\/em><\/p>","protected":false},"excerpt":{"rendered":"

                            Eiginleikar 5-MeO-DMT fr\u00edbasa<\/span><\/span><\/span><\/span><\/h3>\n

                            Samheiti:<\/span><\/span><\/span><\/span><\/strong> 5-metox\u00fd-N,N-d\u00edmet\u00fdltryptam\u00edn <\/span><\/span><\/span><\/span>
                            \nCAS-n\u00famer:<\/span><\/span><\/span><\/span><\/strong> 1019-45-0 <\/span><\/span><\/span><\/span>
                            \nForm\u00fala:<\/span><\/span><\/span><\/span><\/strong> 3-[2-(d\u00edmet\u00fdlam\u00edn\u00f3)et\u00fdl]-5-metox\u00fdind\u00f3l <\/span><\/span><\/span><\/span>
                            \nM\u00f3lmassi:<\/span><\/span><\/span><\/span><\/strong> 218,3 g\/m\u00f3l <\/span><\/span><\/span><\/span>
                            \nHreinleiki:<\/span><\/span><\/span><\/span><\/strong> >97%<\/span><\/span><\/span><\/span><\/p>","protected":false},"featured_media":28719,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[511,381],"product_tag":[326],"class_list":{"0":"post-23497","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-5-meo-dmt-kopen","7":"product_cat-tryptamines","8":"product_tag-nl","10":"first","11":"instock","12":"taxable","13":"shipping-taxable","14":"purchasable","15":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/product\/23497","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/comments?post=23497"}],"version-history":[{"count":4,"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/product\/23497\/revisions"}],"predecessor-version":[{"id":28072,"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/product\/23497\/revisions\/28072"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/media\/28719"}],"wp:attachment":[{"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/media?parent=23497"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/product_brand?post=23497"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/product_cat?post=23497"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/product_tag?post=23497"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}