{"id":23531,"date":"2025-04-13T17:39:56","date_gmt":"2025-04-13T17:39:56","guid":{"rendered":"https:\/\/researchchemicalstore.eu\/?post_type=product&p=23531"},"modified":"2025-10-22T16:39:51","modified_gmt":"2025-10-22T16:39:51","slug":"ept-fumarat-n-etyl-n-propyl-tryptamin","status":"publish","type":"product","link":"https:\/\/researchchemicalstore.eu\/is\/vara\/ept-fumarat-n-etyl-n-propyl-tryptamin\/","title":{"rendered":"EPT f\u00famarat (N-et\u00fdl-N-pr\u00f3p\u00fdltryptam\u00edn)"},"content":{"rendered":"

EPT f\u00famarat (N-et\u00fdl-N-pr\u00f3p\u00fdltryptam\u00edn) \u2013 V\u00edsindaleg v\u00f6rul\u00fdsing<\/span><\/span><\/strong><\/h3>\n

Almennir eiginleikar<\/span><\/span><\/strong><\/h4>\n

EPT f\u00famarat er ranns\u00f3knarefni \u00far flokki tryptam\u00edna, sem einkennist af einst\u00f6ku N-et\u00fdl-N-pr\u00f3p\u00fdl skiptimynstri. \u00deetta efnasamband s\u00fdnir byggingarlega l\u00edkindi vi\u00f0 \u00feekkt tryptam\u00edn eins og DMT og MET, en einkennist af s\u00e9rst\u00f6kum lyfhrifaeiginleikum.<\/span><\/span><\/p>\n

Kjarnauppl\u00fdsingar:<\/span><\/span><\/strong><\/p>\n

    \n
  • \n

    Efnafr\u00e6\u00f0ileg hreinleiki:<\/span><\/span><\/strong> \u00a0>98% (sta\u00f0fest me\u00f0 HPLC-MS)<\/span><\/span><\/p>\n<\/li>\n

  • \n

    Sameindast\u00f6\u00f0ugleiki:<\/span><\/span><\/strong> \u00a0Fr\u00e1b\u00e6r st\u00f6\u00f0ugleiki vegna myndunar f\u00famaratsalts<\/span><\/span><\/p>\n<\/li>\n

  • \n

    Leysni:<\/span><\/span><\/strong> \u00a0Leysanlegt \u00ed vatni og l\u00edfr\u00e6num leysum<\/span><\/span><\/p>\n<\/li>\n

  • \n

    Geymsluskilyr\u00f0i:<\/span><\/span><\/strong> \u00a0Langt\u00edmast\u00f6\u00f0ugleiki vi\u00f0 -20\u00b0C \u00ed \u00f3virku gasi<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

    V\u00edsindaleg notkun<\/span><\/span><\/strong><\/h4>\n
      \n
    1. \n

      Taugalyfjafr\u00e6\u00f0ilegar ranns\u00f3knir:<\/span><\/span><\/strong><\/p>\n

        \n
      • \n

        Milliverkanir ser\u00f3t\u00f3n\u00ednvi\u00f0taka (5-HT1A\/2A\/2C)<\/span><\/span><\/p>\n<\/li>\n

      • \n

        Ranns\u00f3knir \u00e1 h\u00f6mlun \u00e1 m\u00f3n\u00f3am\u00ednox\u00eddasa<\/span><\/span><\/p>\n<\/li>\n

      • \n

        Losunarferli taugabo\u00f0efna<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

      • \n

        Ranns\u00f3knir \u00e1 efnaskiptum:<\/span><\/span><\/strong><\/p>\n

          \n
        • \n

          Efnaskiptaferill lifrarfl\u00edkr\u00f3ms<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Greining \u00e1 v\u00edxlverkun c\u00fdt\u00f3kr\u00f3m P450<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n

        • \n

          Samanbur\u00f0arlyfjafr\u00e6\u00f0i:<\/span><\/span><\/strong><\/p>\n

            \n
          • \n

            Tengsl byggingar og virkni samanbori\u00f0 vi\u00f0 \u00f6nnur N,N-d\u00edalk\u00fdltryptam\u00edn<\/span><\/span><\/p>\n<\/li>\n

          • \n

            Skammta-sv\u00f6runargreining in vitro<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n

            Tilraunalei\u00f0beiningar<\/span><\/span><\/strong><\/h4>\n

            Skammtabil fyrir in vitro ranns\u00f3knir:<\/span><\/span><\/strong><\/p>\n

            \n\n\n\n\n\n\n\n
            Ums\u00f3kn<\/span><\/span><\/th>\nStyrkleikasvi\u00f0<\/span><\/span><\/th>\nBesti r\u00e6ktunart\u00edmi<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
            Vi\u00f0takabinding<\/span><\/span><\/td>\n10 nM \u2013 1 \u03bcM<\/span><\/span><\/td>\n30-60 m\u00edn\u00fatur<\/span><\/span><\/td>\n<\/tr>\n
            Ranns\u00f3knir \u00e1 efnaskiptum<\/span><\/span><\/td>\n1-100 \u03bcM<\/span><\/span><\/td>\n2-4 klukkustundir<\/span><\/span><\/td>\n<\/tr>\n
            Eitur\u00e1hrif frumna<\/span><\/span><\/td>\n10-500 m\u00edkr\u00f3m\u00f3l<\/span><\/span><\/td>\n24-48 klukkustundir<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

            \u00d6ryggisreglur:<\/span><\/span><\/strong><\/p>\n

              \n
            • \n

              Vinni\u00f0 alltaf undir st\u00fdr\u00f0um ranns\u00f3knarstofua\u00f0st\u00e6\u00f0um<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Pers\u00f3nulegur hl\u00edf\u00f0arb\u00fana\u00f0ur (ranns\u00f3knarstofusloppur, n\u00edtr\u00edlhanskar, \u00f6ryggisgleraugu) er nau\u00f0synlegur<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Noti\u00f0 a\u00f0eins \u00ed reykh\u00f3lki vi\u00f0 me\u00f0h\u00f6ndlun leysiefna<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

              St\u00f6\u00f0ugleikag\u00f6gn<\/span><\/span><\/strong><\/h4>\n

              Skjalfest st\u00f6\u00f0ugleiki:<\/span><\/span><\/strong><\/p>\n

                \n
              • \n

                Herbergishitastig: <72 klukkustundir \u00ed lausn<\/span><\/span><\/p>\n<\/li>\n

              • \n

                K\u00e6lt (4\u00b0C): geymist \u00ed 1 viku<\/span><\/span><\/p>\n<\/li>\n

              • \n

                Frosi\u00f0 (-20\u00b0C): st\u00f6\u00f0ugt \u00ed >6 m\u00e1nu\u00f0i<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                R\u00e1\u00f0lag\u00f0ur geymsla:<\/span><\/span><\/strong><\/p>\n

                  \n
                • \n

                  A\u00f0alumb\u00fa\u00f0ir: Gulbr\u00fan glerhettugl\u00f6s me\u00f0 PTFE loki<\/span><\/span><\/p>\n<\/li>\n

                • \n

                  Aukaumb\u00fa\u00f0ir: Loftt\u00e6md innsiglu\u00f0 me\u00f0 k\u00edsilgelpakkningu<\/span><\/span><\/p>\n<\/li>\n

                • \n

                  Geymsluskilyr\u00f0i: -20\u00b0C undir argon andr\u00famslofti<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                  Greiningarvottun<\/span><\/span><\/strong><\/h4>\n

                  Hverri lotu fylgir me\u00f0:<\/span><\/span><\/p>\n

                    \n
                  1. \n

                    \u00cdtarleg HPLC greining (UV\/VIS greining)<\/span><\/span><\/p>\n<\/li>\n

                  2. \n

                    Sta\u00f0festing massagreiningar (LC-MS\/MS)<\/span><\/span><\/p>\n<\/li>\n

                  3. \n

                    Greining \u00e1 leifar af leysiefni<\/span><\/span><\/p>\n<\/li>\n

                  4. \n

                    \u00c1kv\u00f6r\u00f0un vatnsinnihalds (Karl Fischer)<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

                    L\u00f6gleg sta\u00f0a og si\u00f0fr\u00e6\u00f0i<\/span><\/span><\/strong><\/h4>\n

                    Hollenskar regluger\u00f0ir:<\/span><\/span><\/strong><\/p>\n

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                    • \n

                      Ekki innifali\u00f0 \u00ed \u00f3p\u00eduml\u00f6gunum eins og er<\/span><\/span><\/p>\n<\/li>\n

                    • \n

                      Gildir samkv\u00e6mt almennum lyfjal\u00f6gum um ranns\u00f3knarefni<\/span><\/span><\/p>\n<\/li>\n

                    • \n

                      Skylduskr\u00e1ning fyrir v\u00edsindastofnanir<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                      Si\u00f0fer\u00f0islegar lei\u00f0beiningar:<\/span><\/span><\/strong><\/p>\n

                        \n
                      • \n

                        A\u00f0eins til notkunar utan kl\u00edn\u00edskrar ranns\u00f3knar<\/span><\/span><\/p>\n<\/li>\n

                      • \n

                        Banna\u00f0 a\u00f0 gefa m\u00f6nnum e\u00f0a d\u00fdrum<\/span><\/span><\/p>\n<\/li>\n

                      • \n

                        Skyldubundin si\u00f0fer\u00f0ileg endursko\u00f0un fyrir fr\u00e6\u00f0ilegar ranns\u00f3knir<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                        Algengar spurningar<\/span><\/span><\/strong><\/h4>\n

                        Spurning 1: Hvernig ber EPT sig saman vi\u00f0 tryptam\u00edn sem eru svipu\u00f0 hva\u00f0 var\u00f0ar uppbyggingu?<\/span><\/span><\/strong>
                        \n A: Et\u00fdl-pr\u00f3p\u00fdl skiptingin s\u00fdnir einstaka lyfjahvarfaeiginleika, s\u00e9rstaklega \u00ed:<\/span><\/span><\/p>\n

                          \n
                        • \n

                          Fitus\u00e6knipr\u00f3f\u00edl (logP gildi: 2,1)<\/span><\/span><\/p>\n<\/li>\n

                        • \n

                          Pr\u00f3teinbindingargeta (88-92%)<\/span><\/span><\/p>\n<\/li>\n

                        • \n

                          Heila\u00fer\u00f6skuldsgegndr\u00e6pi (hlutfall 0,65 mi\u00f0a\u00f0 vi\u00f0 DMT)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                          Spurning 2: Hva\u00f0a greiningarm\u00f6guleikar eru \u00ed bo\u00f0i \u00ed hef\u00f0bundnum lyfjaskimunum?<\/span><\/span><\/strong>
                          \n A: EPT er ekki greint me\u00f0 hef\u00f0bundnum \u00f3n\u00e6mispr\u00f3fum, en er greinanlegt me\u00f0:<\/span><\/span><\/p>\n

                            \n
                          • \n

                            GC-MS (einkennandi sundrun vi\u00f0 m\/z 130, 144)<\/span><\/span><\/p>\n<\/li>\n

                          • \n

                            LC-QTOF (n\u00e1kv\u00e6m m\u00e6ling \u00e1 sameindamassa)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                            Spurning 3: Eru einhverjar \u00feekktar milliverkanir vi\u00f0 lyf?<\/span><\/span><\/strong>
                            \n A: Fr\u00e6\u00f0ilegar v\u00edxlverkanir eru m\u00f6gulegar me\u00f0:<\/span><\/span><\/p>\n

                              \n
                            • \n

                              MAO-hemlar (styrkjandi \u00e1hrif)<\/span><\/span><\/p>\n<\/li>\n

                            • \n

                              SSRI lyf (samkeppnish\u00f6mlun)<\/span><\/span><\/p>\n<\/li>\n

                            • \n

                              Ge\u00f0rofslyf (samkeppni vi\u00f0taka)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                              Spurning 4: Hver er r\u00e1\u00f0l\u00f6g\u00f0 f\u00f6rgun \u00fargangs?<\/span><\/span><\/strong>
                              \n A: Fylgi\u00f0 reglum um h\u00e6ttulegt \u00fargang:<\/span><\/span><\/p>\n

                                \n
                              • \n

                                Hlutleysa me\u00f0 \u00feynntri salts\u00fdru (0,1M)<\/span><\/span><\/p>\n<\/li>\n

                              • \n

                                Sogi\u00f0 upp me\u00f0 vi\u00f0eigandi efni (t.d. vermik\u00fal\u00edti).<\/span><\/span><\/p>\n<\/li>\n

                              • \n

                                Fargi\u00f0 sem h\u00e6ttulegum efna\u00fargangi (EB-n\u00famer: 404-860-3)<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

                                V\u00edsindalegar heimildir<\/span><\/span><\/strong><\/h4>\n

                                Mikilv\u00e6gar heimildir \u00ed b\u00f3kmenntum:<\/span><\/span><\/p>\n

                                  \n
                                1. \n

                                  Nichols, D. E. (2018). \u201cTengsl milli byggingar og virkni tryptam\u00edna\u201d<\/span><\/span><\/p>\n<\/li>\n

                                2. \n

                                  Brandt o.fl. (2020). \u201cGreiningargreining \u00e1 n\u00fdjum ge\u00f0virkum efnum\u201d<\/span><\/span><\/p>\n<\/li>\n

                                3. \n

                                  Vi\u00f0v\u00f6runarkerfi ESB (2023). \u201c\u00c1h\u00e6ttumat \u00e1 n\u00fdjum tryptam\u00ednaflei\u00f0um\u201d<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

                                  \u00deessi vara er eing\u00f6ngu \u00e6tlu\u00f0 til vi\u00f0urkenndra v\u00edsindaranns\u00f3kna af h\u00e1lfu h\u00e6fs starfsf\u00f3lks. Allar uppl\u00fdsingar eru veittar \u00e1n nokkurrar \u00f3beinnar \u00e1byrg\u00f0ar. Notendur bera \u00e1byrg\u00f0 \u00e1 a\u00f0 fara eftir gildandi reglum.<\/span><\/span><\/em><\/p>","protected":false},"excerpt":{"rendered":"

                                  EPT fumarate properties<\/span><\/span><\/span><\/span><\/span><\/h3>\n

                                  Synonym:<\/span><\/span><\/span><\/span><\/strong> N-ethyl-N-propyltryptamine fumarate <\/span><\/span><\/span><\/span>
                                  \nCAS Number:<\/span><\/span><\/span><\/span><\/strong> n\/a <\/span><\/span><\/span><\/span>
                                  \nFormula:<\/span><\/span><\/span><\/span><\/strong> 3-[2-(ethyl(propyl)amino)ethyl]-1H-indole fumarate <\/span><\/span><\/span><\/span>
                                  \nMolar Mass:<\/span><\/span><\/span><\/span><\/strong> 346.4 g\/mol <\/span><\/span><\/span><\/span>
                                  \nPurity:<\/span><\/span><\/span><\/span><\/strong> >97%<\/span><\/span><\/span><\/span><\/p>\n","protected":false},"featured_media":28774,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[509,381],"product_tag":[326],"class_list":["post-23531","product","type-product","status-publish","has-post-thumbnail","product_cat-ept","product_cat-tryptamines","product_tag-nl","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/product\/23531","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/comments?post=23531"}],"version-history":[{"count":5,"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/product\/23531\/revisions"}],"predecessor-version":[{"id":28071,"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/product\/23531\/revisions\/28071"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/media\/28774"}],"wp:attachment":[{"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/media?parent=23531"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/product_brand?post=23531"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/product_cat?post=23531"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/is\/wp-json\/wp\/v2\/product_tag?post=23531"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}