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GM Fluor - Afbeelding 1

GM Fluor

GM Fluor

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* The information on this page is a summary and is not intended to cover all available information about this medication. It does not cover all possible uses, directions, precautions, drug interactions or adverse effects and is not a substitute for the expertise and judgement of your healthcare professional.

GM Fluoride Sachet 1g – Advanced Research Fluoridation Agent

Product definition

GM-Fluor is a  highly reactive fluorination agent  for organic synthesis, specially developed for  advanced pharmaceutical research & materials science .

✔ 1gr high purity powder
✔ ≥99% chemical purity
✔ Special stabilizers  for safer use
✔ GMP certified production

Laboratory Report (COA) Summary

*Batch #GMF-0427-NL | Tested by FluorChem Labs*
✔ 99.2% purity  (XRD analysis)
✔ <0.1% heavy metals  (ICP-OES)
✔ Moisture content  <0.5% (Karl Fischer)
✔ Reactivity Index : Grade A+

Areas of application

1. Pharmaceutical Synthesis

  • Selective fluoridation of aromatic compounds

  • Prodrug activation studies

2. Materials science

  • Fluoropolymer synthesis

  • Surface modification

3. Analytical Chemistry

  • Isotope labeling studies (¹⁸F/¹⁹F)

  • HPLC retention optimization

Usage protocol

Standard Fluoridation

  1. Dissolve  in anhydrous DMF (50mg/ml)

  2. Add  under argon atmosphere

  3. Reaction temperature : 40-60°C

  4. Duration : 2-4 hours

Safety

•  Always work under inert gas
•  Double gloves  (nitrile + neoprene)
•  Eye/face protection  mandatory

Advantages

✓  Higher yield  than traditional fluorinating agents
✓  Milder reaction conditions  possible
✓  Broad substrate spectrum
✓  Minimal byproduct formation

Disadvantages

⚠ Extremely reactive  with water
⚠ Requires specialized equipment
⚠ Short shelf life  after opening (6 months)
⚠ High cost  compared to alternatives

Frequently Asked Questions (FAQ)

Q: How does GM Fluorine compare to DAST?

ParameterGM FluorineDAST
Reactivity★★★★★★★
Safety★★★★★
Costs€€€€€€

Q: Can I use this for PET scan precursor synthesis?

A:  Yes  – Suitable for ¹⁸F labelling (provided appropriate facilities are available)

Q: What is the storage method?

A:  Vacuum packed  at -20°C under argon

Q: What if there is skin contact?

A: Rinse immediately with  polyethylene glycol 400  + seek medical attention

Harm Reduction Protocol

•   Keep calcium gluconate gel
available •  Do not  use metal tools
•  pH neutralization protocol  for waste

Disclaimer: For use by certified chemists only. Not for amateur chemistry.

🔬Complete safety file?  Email to safety@[company name].nl

Caution: Requires specially ventilated laboratory (fume hood class III).

Research bundle

When ordering >5g:
✓  Free fluoridation protocol book
✓  Access to our reaction database

LEGAL WARNING:  This product is classified as hazardous materials under the  Hazardous Substances Act . Special permits are required for purchase and use.

Recommended Reaction Conditions

Substrate typeTemperatureTimeYield
Aromatics50°C3h85-92%
Alcohols40°C2 hours78-85%
Carboxylic acids60°C4am90-95%

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