{"id":23461,"date":"2025-04-13T17:39:49","date_gmt":"2025-04-13T17:39:49","guid":{"rendered":"https:\/\/researchchemicalstore.eu\/?post_type=product&p=23461"},"modified":"2026-02-02T09:48:08","modified_gmt":"2026-02-02T09:48:08","slug":"4-hodinovy-sladovy-fumarat","status":"publish","type":"product","link":"https:\/\/researchchemicalstore.eu\/sk\/produkt\/4-hodinovy-sladovy-fumarat\/","title":{"rendered":"4-HO-MALT fumar\u00e1t"},"content":{"rendered":"

4-HO-MALT fumar\u00e1t \u2013 vedeck\u00fd popis produktu<\/strong><\/h3>\n

V\u0161eobecn\u00e9 inform\u00e1cie<\/strong><\/h4>\n

4-HO-MALT (4-hydroxy-N-metyl-N-allyltryptam\u00edn) fumar\u00e1t je v\u00fdskumn\u00e1 chemik\u00e1lia triedy tryptam\u00ednov, \u0161truktur\u00e1lne pr\u00edbuzn\u00e1 zl\u00fa\u010denin\u00e1m, ako s\u00fa psiloc\u00edn a 4-HO-MET. T\u00e1to zl\u00fa\u010denina sa pred\u00e1va v\u00fdhradne pre\u00a0vedeck\u00fd v\u00fdskum<\/strong>\u00a0a je\u00a0nie je ur\u010den\u00e9 na \u013eudsk\u00fa spotrebu<\/strong>.<\/p>\n

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Technick\u00e9 \u0161pecifik\u00e1cie<\/strong><\/h4>\n
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  • \n

    Chemick\u00fd n\u00e1zov:<\/strong>\u00a04-hydroxy-N-metyl-N-allyltryptam\u00edn fumar\u00e1t<\/p>\n<\/li>\n

  • \n

    CAS \u010d\u00edslo:<\/strong>\u00a0[Ak je k dispoz\u00edcii]<\/p>\n<\/li>\n

  • \n

    Molekulov\u00fd vzorec:<\/strong>\u00a0C\u2081\u2085H\u2082\u2080N\u2082O\u2082 \u00b7 C\u2084H\u2084O\u2084<\/p>\n<\/li>\n

  • \n

    Molekulov\u00e1 hmotnos\u0165:<\/strong>\u00a0350,37 g\/mol<\/p>\n<\/li>\n

  • \n

    \u010distota:<\/strong>\u00a0\u226598% (overen\u00e9 pomocou HPLC-MS)<\/p>\n<\/li>\n

  • \n

    Vzh\u013ead:<\/strong>\u00a0Biely a\u017e svetlo\u017elt\u00fd kry\u0161talick\u00fd pr\u00e1\u0161ok<\/p>\n<\/li>\n

  • \n

    Rozpustnos\u0165:<\/strong>\u00a0Rozpustn\u00fd vo vode (20 mg\/ml) a etanole<\/p>\n<\/li>\n

  • \n

    Stabilita:<\/strong>\u00a0>12 mesiacov pri skladovan\u00ed do -20 \u00b0C vo vzduchotesnom obale<\/p>\n<\/li>\n<\/ul>\n

    \n

    Vedeck\u00e9 aplik\u00e1cie<\/strong><\/h3>\n

    4-HO-MALT fumar\u00e1t sa pou\u017e\u00edva vo v\u00fdskume na:<\/p>\n

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    1. \n

      Neurofarmakologick\u00e9 \u0161t\u00fadie:<\/strong><\/p>\n

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      • \n

        V\u00e4zbov\u00e9 vlastnosti na seroton\u00ednov\u00e9 (5-HT\u2082A\/5-HT\u2081A) receptory<\/p>\n<\/li>\n

      • \n

        Porovn\u00e1vacie \u0161t\u00fadie s klasick\u00fdmi psychedelikami<\/p>\n<\/li>\n<\/ul>\n<\/li>\n

      • \n

        Behavior\u00e1lny v\u00fdskum:<\/strong><\/p>\n

          \n
        • \n

          \u00da\u010dinky na senzorick\u00e9 spracovanie v zvierac\u00edch modeloch<\/p>\n<\/li>\n

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          Testovanie spr\u00e1vania s\u00favisiaceho s \u00fazkos\u0165ou v otvorenom poli<\/p>\n<\/li>\n<\/ul>\n<\/li>\n

        • \n

          Metabolick\u00e9 \u0161t\u00fadie:<\/strong><\/p>\n

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          • \n

            \u0160t\u00fadia metabolizmu v pe\u010deni in vitro<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n

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            Experiment\u00e1lne parametre<\/strong><\/h3>\n

            D\u00e1vkovanie (pre predklinick\u00e9 \u0161t\u00fadie)<\/strong><\/h4>\n
            \n\n\n\n\n\n\n\n
            Sp\u00f4sob podania<\/th>\nTestovan\u00e1 koncentr\u00e1cia<\/th>\nRozp\u00fa\u0161\u0165adlo<\/th>\n<\/tr>\n<\/thead>\n
            Or\u00e1lne<\/td>\n5 \u2013 15 mg\/kg<\/td>\nPBS pufor<\/td>\n<\/tr>\n
            Intraperitone\u00e1lne<\/td>\n2 \u2013 8 mg\/kg<\/td>\nSteriln\u00e1 H\u2082O<\/td>\n<\/tr>\n
            In vitro<\/td>\n1 \u2013 100 \u03bcM<\/td>\nDMSO <0,1%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

            Pozn\u00e1mka: D\u00e1vkovanie je zalo\u017een\u00e9 na \u0161truktur\u00e1lne pr\u00edbuzn\u00fdch zl\u00fa\u010denin\u00e1ch. V\u017edy vykonajte pilotn\u00e9 \u0161t\u00fadie.<\/em><\/p>\n

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            Bezpe\u010dnostn\u00fd protokol<\/strong><\/h3>\n

            Potenci\u00e1lne rizik\u00e1<\/strong><\/h4>\n
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            • \n

              Ak\u00fatna toxicita:<\/strong>\u00a0LD\u2085\u2080 nebola stanoven\u00e1 \u2013 pou\u017eite princ\u00edp ALARA<\/p>\n<\/li>\n

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              Ved\u013eaj\u0161ie \u00fa\u010dinky:<\/strong><\/p>\n

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              • \n

                Zv\u00fd\u0161en\u00e1 pohybov\u00e1 aktivita pri n\u00edzkych d\u00e1vkach<\/p>\n<\/li>\n

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                Katalepsia pri vy\u0161\u0161\u00edch koncentr\u00e1ci\u00e1ch<\/p>\n<\/li>\n<\/ul>\n<\/li>\n

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                Nebezpe\u010denstvo prachu:<\/strong>\u00a0Pri manipul\u00e1cii s pr\u00e1\u0161kom v\u017edy noste masku P2<\/p>\n<\/li>\n<\/ul>\n

                Podmienky skladovania<\/strong><\/h4>\n
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                • \n

                  Skladujte pri teplote -20 \u00b0C v arg\u00f3novej atmosf\u00e9re<\/p>\n<\/li>\n

                • \n

                  Pou\u017e\u00edvajte jant\u00e1rov\u00e9 sklenen\u00e9 f\u013ea\u0161ti\u010dky<\/p>\n<\/li>\n

                • \n

                  Trvanlivos\u0165: 24 mesiacov pri spr\u00e1vnom skladovan\u00ed<\/p>\n<\/li>\n<\/ul>\n

                  \n

                  Analytick\u00e9 \u00fadaje<\/strong><\/h3>\n

                  Kontrola kvality (\u0161ar\u017ea XYZ-123)<\/strong><\/h4>\n
                  \n\n\n\n\n\n\n\n
                  Test<\/th>\nV\u00fdsledok<\/th>\nMet\u00f3da<\/th>\n<\/tr>\n<\/thead>\n
                  \u010cistota<\/td>\n98.7%<\/td>\nHPLC-UV (254 nm)<\/td>\n<\/tr>\n
                  \u0164a\u017ek\u00e9 kovy<\/td>\n<10 ppm<\/td>\nICP-MS<\/td>\n<\/tr>\n
                  Obsah vody<\/td>\n0.8%<\/td>\nKarl Fischer<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n
                  \n

                  \u010casto kladen\u00e9 ot\u00e1zky (FAQ)<\/strong><\/h3>\n

                  1. Je t\u00e1to l\u00e1tka regulovan\u00e1 v E\u00da?<\/strong><\/p>\n

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                  • \n

                    Status sa l\u00ed\u0161i v z\u00e1vislosti od \u010dlensk\u00e9ho \u0161t\u00e1tu. V Holandsku m\u00f4\u017ee spada\u0165 pod z\u00e1kon o \u00f3piu. Pre\u0161tudujte si miestne predpisy.<\/p>\n<\/li>\n<\/ul>\n

                    2. Ktor\u00e9 analytick\u00e9 met\u00f3dy sa odpor\u00fa\u010daj\u00fa?<\/strong><\/p>\n

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                    • \n

                      HPLC-MS na kvantifik\u00e1ciu<\/p>\n<\/li>\n

                    • \n

                      NMR (\u00b9H\/\u00b9\u00b3C) pre potvrdenie \u0161trukt\u00fary<\/p>\n<\/li>\n<\/ul>\n

                      3. M\u00f4\u017eem dosta\u0165 kartu bezpe\u010dnostn\u00fdch \u00fadajov?<\/strong><\/p>\n

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                      • \n

                        \u00c1no, pre akademick\u00e9 in\u0161tit\u00facie je k dispoz\u00edcii roz\u0161\u00edren\u00e1 karta bezpe\u010dnostn\u00fdch \u00fadajov.<\/p>\n<\/li>\n<\/ul>\n

                        4. Ak\u00e1 je stabilita v roztoku?<\/strong><\/p>\n

                          \n
                        • \n

                          Skladujte v PBS maxim\u00e1lne 48 hod\u00edn pri teplote 4 \u00b0C. Pre dlh\u0161ie skladovanie zmrazte pri teplote -80 \u00b0C.<\/p>\n<\/li>\n<\/ul>\n

                          \n

                          Inform\u00e1cie o objedn\u00e1vke<\/strong><\/h3>\n
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                          • \n

                            Minim\u00e1lna objedn\u00e1vka:<\/strong>\u00a0100 mg<\/p>\n<\/li>\n

                          • \n

                            Balenie:<\/strong>\u00a0Pod arg\u00f3nom v jant\u00e1rovej HPLC f\u013ea\u0161ti\u010dke<\/p>\n<\/li>\n

                          • \n

                            Doprava:<\/strong>\u00a0Chladen\u00e1 preprava s kockami \u013eadu<\/p>\n<\/li>\n<\/ul>\n

                            UPOZORNENIE: Tento produkt je ur\u010den\u00fd len na v\u00fdskumn\u00e9 \u00fa\u010dely kvalifikovan\u00fdm person\u00e1lom v akreditovan\u00fdch laborat\u00f3ri\u00e1ch. Nie je ur\u010den\u00fd na diagnostick\u00e9 ani terapeutick\u00e9 pou\u017eitie.<\/em><\/p>\n

                            V pr\u00edpade v\u00fdskumnej spolupr\u00e1ce alebo hromadn\u00fdch objedn\u00e1vok kontaktujte, pros\u00edm, na\u0161e vedeck\u00e9 oddelenie.<\/p>","protected":false},"excerpt":{"rendered":"

                            4-HO-MALT fumar\u00e1t \u2013 vedeck\u00fd popis produktu V\u0161eobecn\u00e9 inform\u00e1cie 4-HO-MALT (4-hydroxy-N-metyl-N-allyltryptam\u00edn) fumar\u00e1t je v\u00fdskumn\u00e1 chemik\u00e1lia triedy tryptam\u00ednov, \u0161truktur\u00e1lne pr\u00edbuzn\u00e1 l\u00e1tkam<\/p>","protected":false},"featured_media":28703,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[543,381],"product_tag":[326],"class_list":{"0":"post-23461","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-4-ho-malt","7":"product_cat-tryptamines","8":"product_tag-nl","10":"first","11":"instock","12":"taxable","13":"shipping-taxable","14":"purchasable","15":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product\/23461","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/comments?post=23461"}],"version-history":[{"count":3,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product\/23461\/revisions"}],"predecessor-version":[{"id":26630,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product\/23461\/revisions\/26630"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/media\/28703"}],"wp:attachment":[{"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/media?parent=23461"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product_brand?post=23461"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product_cat?post=23461"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product_tag?post=23461"}],"curies":[{"name":"pracovn\u00fd list","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}