{"id":23655,"date":"2025-04-13T17:40:11","date_gmt":"2025-04-13T17:40:11","guid":{"rendered":"https:\/\/researchchemicalstore.eu\/?post_type=product&p=23655"},"modified":"2025-10-22T14:57:47","modified_gmt":"2025-10-22T14:57:47","slug":"idra-21-10-mg-pelety","status":"publish","type":"product","link":"https:\/\/researchchemicalstore.eu\/sk\/produkt\/idra-21-10-mg-pelety\/","title":{"rendered":"IDRA-21 10 MG pelety"},"content":{"rendered":"

IDRA-21 10 MG pelety \u2013 vedeck\u00fd popis a pou\u017e\u00edvate\u013esk\u00e1 pr\u00edru\u010dka<\/span><\/span><\/strong><\/h3>\n

Popis produktu<\/span><\/span><\/strong><\/h4>\n

IDRA-21 (10 mg pelety)<\/span><\/span><\/strong> \u00a0je potenci\u00e1l\u00a0 <\/span><\/span>Potenci\u00e1tor AMPA receptora<\/span><\/span><\/strong> \u00a0patriaci do triedy\u00a0 <\/span><\/span>nootropn\u00e9 a neuroprotekt\u00edvne v\u00fdskumn\u00e9 chemik\u00e1lie<\/span><\/span><\/strong> . Funguje tak, \u017ee posil\u0148uje signaliz\u00e1ciu indukovan\u00fa glutam\u00e1tom v mozgu, \u010do m\u00f4\u017ee vies\u0165 k zlep\u0161eniu kognit\u00edvnych funkci\u00ed, neuroplasticity a potenci\u00e1lne neurorekonvalescencie.<\/span><\/span><\/p>\n

Tieto pelety s\u00fa\u00a0 <\/span><\/span>vysoko \u010dist\u00fd (\u226598%)<\/span><\/span><\/strong> , \u0161tandardizovan\u00e9 d\u00e1vkovanie a ur\u010den\u00e9 v\u00fdlu\u010dne na\u00a0 <\/span><\/span>vedeck\u00fd v\u00fdskum a predklinick\u00e9 \u0161t\u00fadie<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n

\n

Pou\u017eitie a aplik\u00e1cie<\/span><\/span><\/strong><\/h3>\n

IDRA-21 sa sk\u00fama z h\u013eadiska jeho mo\u017en\u00fdch \u00fa\u010dinkov na:<\/span><\/span><\/p>\n

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  1. \n

    Kognit\u00edvne vylep\u0161enie<\/span><\/span><\/strong> \u00a0\u2013 M\u00f4\u017ee zv\u00fd\u0161i\u0165 bdelos\u0165, schopnos\u0165 u\u010di\u0165 sa a konsolid\u00e1ciu pam\u00e4te.<\/span><\/span><\/p>\n<\/li>\n

  2. \n

    Neuroprotekcia<\/span><\/span><\/strong> \u00a0\u2013 Potenci\u00e1lny ochrann\u00fd \u00fa\u010dinok pri neurodegenerat\u00edvnych ochoreniach (napr. Alzheimerova choroba, mozgov\u00e1 pr\u00edhoda).<\/span><\/span><\/p>\n<\/li>\n

  3. \n

    Neurologick\u00e9 zotavenie<\/span><\/span><\/strong> \u00a0\u2013 M\u00f4\u017ee podporova\u0165 synaptick\u00fa plasticitu po poranen\u00ed mozgu.<\/span><\/span><\/p>\n<\/li>\n

  4. \n

    Vedeck\u00fd v\u00fdskum<\/span><\/span><\/strong> \u00a0\u2013 \u0160t\u00fadium modul\u00e1cie AMPA receptora a glutam\u00e1tovej signaliz\u00e1cie.<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

    \u26a0\u00a0Nie je schv\u00e1len\u00e9 na pou\u017eitie u \u013eud\u00ed ani vo veterin\u00e1rnej medic\u00edne \u2013 Len na \u0161t\u00fadie in vitro a kontrolovan\u00e9 predklinick\u00e9 \u0161t\u00fadie.<\/span><\/span><\/strong><\/p>\n

    \n

    D\u00e1vkovanie a bezpe\u010dnostn\u00e9 pokyny<\/span><\/span><\/strong><\/h3>\n
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    • \n

      Sk\u00fa\u0161an\u00e1 d\u00e1vka (in vitro\/predklinick\u00e1): <\/span><\/span><\/strong>\u00a05 \u2013 20 mg\/kg<\/span><\/span><\/strong> \u00a0(v z\u00e1vislosti od modelu).<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Roztok peliet:<\/span><\/span><\/strong> \u00a0M\u00f4\u017ee sa rozpusti\u0165 v\u00a0 <\/span><\/span>destilovan\u00e1 voda alebo DMSO<\/span><\/span><\/strong> \u00a0pre experimenty.<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Administrat\u00edva:<\/span><\/span><\/strong> \u00a0Or\u00e1lne (zvieracie modely) alebo priamo v bunkov\u00fdch kult\u00farach.<\/span><\/span><\/p>\n<\/li>\n

    • \n

      Frekvencia:<\/span><\/span><\/strong> \u00a0Jednorazov\u00e1 d\u00e1vka pre ak\u00fatny \u00fa\u010dinok; dlhodob\u00e9 \u0161t\u00fadie vy\u017eaduj\u00fa starostliv\u00e9 monitorovanie.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

      \ud83d\udea8\u00a0Pozn\u00e1mka:<\/span><\/span><\/strong><\/p>\n

        \n
      • \n

        \u017diadna aplik\u00e1cia na \u010dloveka<\/span><\/span><\/strong> \u00a0\u2013 \u017diadne \u00fadaje o bezpe\u010dnosti pre pou\u017eitie u \u013eud\u00ed.<\/span><\/span><\/p>\n<\/li>\n

      • \n

        Vysok\u00e9 d\u00e1vky m\u00f4\u017eu sp\u00f4sobi\u0165 neuroexcitotoxicitu.<\/span><\/span><\/strong><\/p>\n<\/li>\n

      • \n

        Vyhnite sa kombin\u00e1cii s in\u00fdmi modul\u00e1tormi glutam\u00e1tu.<\/span><\/span><\/strong><\/p>\n<\/li>\n<\/ul>\n

        \n

        Nev\u00fdhody a rizik\u00e1<\/span><\/span><\/strong><\/h3>\n
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        • \n

          Nadmern\u00e1 stimul\u00e1cia neur\u00f3nov<\/span><\/span><\/strong> \u00a0(riziko excitotoxicity v pr\u00edpade pred\u00e1vkovania).<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Mo\u017en\u00e1 \u00fazkos\u0165 alebo nepokoj<\/span><\/span><\/strong> \u00a0u citliv\u00fdch modelov.<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Obmedzen\u00e9 dlhodob\u00e9 \u00fadaje<\/span><\/span><\/strong> \u00a0o tolerancii a ne\u017eiaducich \u00fa\u010dinkoch.<\/span><\/span><\/p>\n<\/li>\n

        • \n

          Nie je vhodn\u00e9 na chronick\u00e9 u\u017e\u00edvanie<\/span><\/span><\/strong> \u00a0bez rozsiahlych \u0161t\u00fadi\u00ed toxicity.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

          \n

          \u010casto kladen\u00e9 ot\u00e1zky (FAQ)<\/span><\/span><\/strong><\/h3>\n

          1. Je IDRA-21 v Holandsku leg\u00e1lny?<\/span><\/span><\/strong><\/h4>\n

          \u00c1no, ale len pre\u00a0 <\/span><\/span>vedeck\u00fd v\u00fdskum<\/span><\/span><\/strong> . Nespad\u00e1 pod z\u00e1kon o \u00f3piu, ale nie je schv\u00e1len\u00fd ani ako liek.<\/span><\/span><\/p>\n

          2. Ako presne funguje IDRA-21?<\/span><\/span><\/strong><\/h4>\n

          To\u00a0 <\/span><\/span>zvy\u0161uje odpove\u010f AMPA receptora<\/span><\/span><\/strong> , \u010d\u00edm sa glutam\u00e1tov\u00e1 signaliz\u00e1cia predl\u017euje a zintenz\u00edvni. To m\u00f4\u017ee vies\u0165 k zlep\u0161eniu synaptickej komunik\u00e1cie.<\/span><\/span><\/p>\n

          3. D\u00e1 sa IDRA-21 porovna\u0165 s in\u00fdmi nootropikami?<\/span><\/span><\/strong><\/h4>\n

          M\u00e1 jedine\u010dn\u00fd mechanizmus \u00fa\u010dinku, ale\u00a0 <\/span><\/span>podobn\u00e9 ciele ako racetamy alebo ampak\u00edny<\/span><\/span><\/strong> \u00a0(napr. Sunifiram).<\/span><\/span><\/p>\n

          4. S\u00fa zn\u00e1me nejak\u00e9 interakcie?<\/span><\/span><\/strong><\/h4>\n
            \n
          • \n

            Antagonisty NMDA<\/span><\/span><\/strong> \u00a0(napr. memant\u00edn) \u2013 Potenci\u00e1lne ne\u017eiaduce \u00fa\u010dinky.<\/span><\/span><\/p>\n<\/li>\n

          • \n

            GABAergn\u00e9 l\u00e1tky<\/span><\/span><\/strong> \u00a0(napr. benzodiazep\u00edny) \u2013 M\u00f4\u017eu zni\u017eova\u0165 anxiolytick\u00e9 \u00fa\u010dinky.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

            \n

            Laborat\u00f3rna spr\u00e1va a kontrola kvality<\/span><\/span><\/strong><\/h3>\n
              \n
            • \n

              HPLC anal\u00fdza: <\/span><\/span><\/strong>\u00a0\u010cistota \u226598%<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n<\/li>\n

            • \n

              \u017diadne detekovate\u013en\u00e9 zvy\u0161ky \u0165a\u017ek\u00fdch kovov ani rozp\u00fa\u0161\u0165adiel<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Homog\u00e9nna formul\u00e1cia peliet<\/span><\/span><\/strong> \u00a0pre konzistentn\u00e9 d\u00e1vkovanie.<\/span><\/span><\/p>\n<\/li>\n

            • \n

              Certifik\u00e1cia \u0161ar\u017ee<\/span><\/span><\/strong> \u00a0k dispoz\u00edcii pre v\u00fdskumn\u00e9 in\u0161tit\u00facie.<\/span><\/span><\/p>\n<\/li>\n<\/ul>\n

              \n

              Odpor\u00fa\u010dan\u00e9 v\u00fdskumn\u00e9 scen\u00e1re<\/span><\/span><\/strong><\/h3>\n
                \n
              1. \n

                Kognit\u00edvne \u0161t\u00fadie<\/span><\/span><\/strong> \u00a0\u2013 \u00da\u010dinky na pam\u00e4\u0165 a u\u010denie na zvierac\u00edch modeloch.<\/span><\/span><\/p>\n<\/li>\n

              2. \n

                Neuroprotekt\u00edvny v\u00fdskum<\/span><\/span><\/strong> \u00a0\u2013 Potenci\u00e1lna \u00faloha pri ischemickom poranen\u00ed (modely cievnej mozgovej pr\u00edhody).<\/span><\/span><\/p>\n<\/li>\n

              3. \n

                Elektrofyziol\u00f3gia<\/span><\/span><\/strong> \u00a0\u2013 Merania odpovede AMPA receptorov v neuron\u00e1lnych kult\u00farach.<\/span><\/span><\/p>\n<\/li>\n<\/ol>\n

                \ud83d\udd2c\u00a0Len na kontrolovan\u00e9 laborat\u00f3rne pou\u017eitie \u2013 Nie na rekrea\u010dn\u00e9 pou\u017eitie!<\/span><\/span><\/strong><\/p>\n

                ","protected":false},"excerpt":{"rendered":"

                Vlastnosti peliet IDRA-21<\/span><\/span><\/h3>\n

                Synonymum<\/span><\/span><\/strong> : 7-chl\u00f3r-3-metyl-3,4-dihydro-2H-1,2,4-benzotiadiaz\u00edn-1,1-dioxid <\/span><\/span>
                \nCAS <\/span><\/span><\/strong> \u010c\u00edslo<\/span><\/span><\/strong> : 22503-72-6 <\/span><\/span>
                \nVzorec<\/span><\/span><\/strong> : C8H9CIN202S <\/span><\/span>
                \nMol\u00e1rna hmotnos\u0165<\/span><\/span><\/strong> : 232,6 g\/mol <\/span><\/span>
                \n\u010cistota<\/span><\/span><\/strong> : >97%<\/span><\/span><\/p>","protected":false},"featured_media":28802,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[548,549,330,324],"product_tag":[326],"class_list":["post-23655","product","type-product","status-publish","has-post-thumbnail","product_cat-idra-21","product_cat-idra-21-pellets","product_cat-nootropics","product_cat-pellets-for-pellet","product_tag-nl","first","instock","taxable","shipping-taxable","purchasable","product-type-variable"],"_links":{"self":[{"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product\/23655","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/comments?post=23655"}],"version-history":[{"count":5,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product\/23655\/revisions"}],"predecessor-version":[{"id":28058,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product\/23655\/revisions\/28058"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/media\/28802"}],"wp:attachment":[{"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/media?parent=23655"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product_brand?post=23655"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product_cat?post=23655"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product_tag?post=23655"}],"curies":[{"name":"pracovn\u00fd list","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}