{"id":23688,"date":"2025-04-13T17:40:15","date_gmt":"2025-04-13T17:40:15","guid":{"rendered":"https:\/\/researchchemicalstore.eu\/?post_type=product&p=23688"},"modified":"2025-11-17T11:29:16","modified_gmt":"2025-11-17T11:29:16","slug":"klonazolam-06-mg-blistre-po-10-peliet","status":"publish","type":"product","link":"https:\/\/researchchemicalstore.eu\/sk\/produkt\/klonazolam-06-mg-blistre-po-10-peliet\/","title":{"rendered":"Klonazolam 0,6 MG blistre s 10 peletami"},"content":{"rendered":"

Blistre s obsahom klonazolamu 0,6 mg \u2013 ultra\u00fa\u010dinn\u00fd thienotriazolobenzodiazep\u00edn pre pokro\u010dil\u00fd v\u00fdskum<\/span><\/span><\/strong><\/h1>\n

N\u00e1zov produktu:<\/span><\/span><\/strong> Klonazolam 0,6 mg pelety \u2013 blistrov\u00e9 balenie <\/span><\/span>
\n\u00da\u010dinn\u00e1 l\u00e1tka:<\/span><\/span><\/strong> klonazolam <\/span><\/span>
\nChemick\u00e1 trieda:<\/span><\/span><\/strong> Triazolobenzodiazep\u00edny <\/span><\/span>
\nMolekul\u00e1rny vzorec:<\/span><\/span><\/strong> C17H12ClN5O2 <\/span><\/span>
\nMolekulov\u00e1 hmotnos\u0165:<\/span><\/span><\/strong> 353,77 g\/mol <\/span><\/span>
\nD\u00e1vkovanie na jednu peletu:<\/span><\/span><\/strong> 0,6 mg <\/span><\/span>
\nFormul\u00e1r:<\/span><\/span><\/strong> Lisovan\u00e9 pelety <\/span><\/span>
\nBalenie:<\/span><\/span><\/strong> Blister s 10 peletami <\/span><\/span>
\nIndik\u00e1cia:<\/span><\/span><\/strong> Len na laborat\u00f3rne a analytick\u00e9 pou\u017eitie<\/span><\/span><\/p>\n

\n

\ud83e\uddec \u010co je klonazolam?<\/span><\/span><\/strong><\/h2>\n

Klonazolam je <\/span><\/span>ultra\u00fa\u010dinn\u00fd triazolobenzodiazep\u00edn<\/span><\/span><\/strong> odvoden\u00fd z klonazepamu a alprazolamu. Je zn\u00e1my svojou <\/span><\/span>ve\u013emi n\u00edzka \u00fa\u010dinn\u00e1 d\u00e1vka<\/span><\/span><\/strong> a bol \u0161tudovan\u00fd v laborat\u00f3riu kv\u00f4li jeho <\/span><\/span>siln\u00fd agonista receptora GABA-A<\/span><\/span><\/strong> , <\/span><\/span>dlh\u00fd pol\u010das rozpadu<\/span><\/span><\/strong> a <\/span><\/span>vysok\u00e1 v\u00e4zbov\u00e1 afinita<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n

D\u00e1vkovanie 0,6 mg peliet je z\u00e1merne n\u00edzke vzh\u013eadom na v\u00fdnimo\u010dn\u00fa \u00fa\u010dinnos\u0165 klonazolamu \u2013 ide\u00e1lne pre <\/span><\/span>\u0161t\u00fadie presn\u00e9ho d\u00e1vkovania, v\u00fdskum v\u00e4zby na receptory<\/span><\/span><\/strong> a porovnania v r\u00e1mci \u0161truktur\u00e1lnej triedy benzodiazep\u00ednov.<\/span><\/span><\/p>\n

\n

\u2705 Aplik\u00e1cie vo vedeckom v\u00fdskume<\/span><\/span><\/strong><\/h2>\n
    \n
  • \u0160t\u00fadie v\u00e4zby na receptory (podtypy GABA-A)<\/span><\/span><\/strong><\/li>\n
  • Farmakokinetick\u00e1 skr\u00edningov\u00e1 \u0161t\u00fadia (in vitro)<\/span><\/span><\/strong><\/li>\n
  • Anal\u00fdza toxicity a stability v laborat\u00f3rnych podmienkach<\/span><\/span><\/strong><\/li>\n
  • Porovn\u00e1vac\u00ed v\u00fdskum SAR v r\u00e1mci benzoov\u00fdch a triazolov\u00fdch deriv\u00e1tov<\/span><\/span><\/strong><\/li>\n
  • Referen\u010dn\u00e1 vzorka pre analytick\u00e9 zariadenie (HPLC\/GC-MS)<\/span><\/span><\/strong><\/li>\n<\/ul>\n

    \u26a0\ufe0f Pozn\u00e1mka:<\/span><\/span><\/strong> Nie je vhodn\u00e9 na \u013eudsk\u00fa spotrebu. Len na pou\u017eitie v akreditovan\u00fdch v\u00fdskumn\u00fdch zariadeniach.<\/span><\/span><\/p><\/blockquote>\n

    \n

    \u26a0\ufe0f Mo\u017en\u00e9 nev\u00fdhody a rizik\u00e1<\/span><\/span><\/strong><\/h2>\n
      \n
    • Extr\u00e9mne n\u00edzky prah d\u00e1vky<\/span><\/span><\/strong> \u2013 riziko pred\u00e1vkovania pri nespr\u00e1vnom pou\u017eit\u00ed<\/span><\/span><\/li>\n
    • Ve\u013emi dlh\u00e9 trvanie \u00fa\u010dinku<\/span><\/span><\/strong> \u2013 relevantn\u00e9 pre \u0161t\u00fadie metabolizmu a rozkladu<\/span><\/span><\/li>\n
    • Siln\u00fd sedat\u00edvny, amnestick\u00fd a svalovo-relaxa\u010dn\u00fd profil<\/span><\/span><\/strong><\/li>\n
    • Predpisy sa l\u00ed\u0161ia v z\u00e1vislosti od krajiny (mo\u017eno s\u00fa regulovan\u00e9)<\/span><\/span><\/strong><\/li>\n
    • Riziko z\u00e1vislosti, rebound nespavosti a kognit\u00edvneho po\u0161kodenia pri zneu\u017e\u00edvan\u00ed<\/span><\/span><\/strong><\/li>\n<\/ul>\n
      \n

      \ud83e\uddea Laborat\u00f3rne \u00fadaje<\/span><\/span><\/strong><\/h2>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
      Charakteristick\u00fd<\/span><\/span><\/th>\n\u0160pecifik\u00e1cia<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
      \u00da\u010dinn\u00e1 l\u00e1tka<\/span><\/span><\/td>\nKlonazolam (\u010distota \u226599%, overen\u00e1 HPLC)<\/span><\/span><\/td>\n<\/tr>\n
      Formul\u00e1r<\/span><\/span><\/td>\nLisovan\u00e9 pelety (\u0161tandardn\u00e1 ve\u013ekos\u0165)<\/span><\/span><\/td>\n<\/tr>\n
      D\u00e1vkovanie na peletu<\/span><\/span><\/td>\n0,6 mg<\/span><\/span><\/td>\n<\/tr>\n
      Balenie<\/span><\/span><\/td>\nBlister s 10 peletami<\/span><\/span><\/td>\n<\/tr>\n
      Farba<\/span><\/span><\/td>\nSvetlo\u017elt\u00e1 a\u017e b\u00e9\u017eov\u00e1<\/span><\/span><\/td>\n<\/tr>\n
      Rozpustnos\u0165<\/span><\/span><\/td>\n\u013dahko rozpustn\u00fd v etanole, DMSO<\/span><\/span><\/td>\n<\/tr>\n
      Rady pre skladovanie<\/span><\/span><\/td>\nSkladujte na chladnom (2\u20138 \u00b0C), suchom a tmavom mieste.<\/span><\/span><\/td>\n<\/tr>\n
      Stabilita<\/span><\/span><\/td>\nA\u017e 24 mesiacov pri spr\u00e1vnom skladovan\u00ed<\/span><\/span><\/td>\n<\/tr>\n
      Certifik\u00e1t pravosti<\/span><\/span><\/td>\nK dispoz\u00edcii na po\u017eiadanie<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
      \n

      \ud83d\udca1 Odpor\u00fa\u010dan\u00e9 pr\u00edpady pou\u017eitia<\/span><\/span><\/strong><\/h2>\n\n\n\n\n\n\n\n\n\n
      Oblas\u0165 v\u00fdskumu<\/span><\/span><\/th>\nAplik\u00e1cia<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
      Neurofarmakol\u00f3gia<\/span><\/span><\/td>\nTest v\u00e4zby na podtypy receptorov GABA-A<\/span><\/span><\/td>\n<\/tr>\n
      Analytick\u00e1 ch\u00e9mia<\/span><\/span><\/td>\nValid\u00e1cia detek\u010dn\u00fdch met\u00f3d (LC-MS)<\/span><\/span><\/td>\n<\/tr>\n
      V\u00fdskum SAR<\/span><\/span><\/td>\nPorovnanie s in\u00fdmi triazolobenzodiazep\u00ednmi<\/span><\/span><\/td>\n<\/tr>\n
      \u0160t\u00fadie stability<\/span><\/span><\/td>\nPod vplyvom teploty a UV \u017eiarenia<\/span><\/span><\/td>\n<\/tr>\n
      \u0160t\u00fadia d\u00e1vkovania<\/span><\/span><\/td>\nVyhodnotenie mechanizmov \u00fa\u010dinku pri n\u00edzkych d\u00e1vkach<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
      \n

      \u2753 \u010casto kladen\u00e9 ot\u00e1zky (FAQ)<\/span><\/span><\/strong><\/h2>\n

      1. Pre\u010do iba 0,6 mg na peletu?<\/span><\/span><\/strong>
      \n Klonazolam je <\/span><\/span>ve\u013emi siln\u00fd<\/span><\/span><\/strong> \u2013 siln\u00e9 \u00fa\u010dinky sa m\u00f4\u017eu vyskytn\u00fa\u0165 u\u017e pri d\u00e1vke 0,25 \u2013 0,5 mg. D\u00e1vka 0,6 mg umo\u017e\u0148uje laborat\u00f3rnu anal\u00fdzu s minim\u00e1lnou chybovos\u0165ou.<\/span><\/span><\/p>\n

      2. Je klonazolam leg\u00e1lny?<\/span><\/span><\/strong>
      \n Z\u00e1vis\u00ed to od va\u0161ej krajiny alebo regi\u00f3nu. V mnoh\u00fdch krajin\u00e1ch sa to pova\u017euje za kontrolovan\u00fa l\u00e1tku. Pred pou\u017eit\u00edm alebo dr\u017ebou si v\u017edy overte miestne z\u00e1kony.<\/span><\/span><\/p>\n

      3. Je t\u00e1to l\u00e1tka vhodn\u00e1 na pou\u017eitie u \u013eud\u00ed? <\/span><\/span><\/strong>
      \nNie.<\/span><\/span><\/strong> Tento produkt je ur\u010den\u00fd pre <\/span><\/span>vedeck\u00fd v\u00fdskum<\/span><\/span><\/strong> iba. Ak\u00e9ko\u013evek in\u00e9 pou\u017eitie je <\/span><\/span>nebezpe\u010dn\u00e9 a zak\u00e1zan\u00e9<\/span><\/span><\/strong> .<\/span><\/span><\/p>\n

      4. Je k dispoz\u00edcii certifik\u00e1t anal\u00fdzy (COA)?<\/span><\/span><\/strong>
      \n \u00c1no, a <\/span><\/span>Certifik\u00e1t pravosti<\/span><\/span><\/strong> s inform\u00e1ciami \u0161pecifick\u00fdmi pre dan\u00fa \u0161ar\u017eu s\u00fa k dispoz\u00edcii na po\u017eiadanie.<\/span><\/span><\/p>\n

      5. Ako m\u00e1m skladova\u0165 tieto pelety?<\/span><\/span><\/strong>
      \n Uskladnite ich v p\u00f4vodnom blistri. <\/span><\/span>chladnom, suchom a tmavom mieste<\/span><\/span><\/strong> miesto. V\u010faka tomu zostan\u00fa pelety stabiln\u00e9 a d\u00e1vkovanie bude jednoduch\u00e9.<\/span><\/span><\/p>\n

      \n

      \ud83d\udce6 Preh\u013ead produktu<\/span><\/span><\/strong><\/h2>\n\n\n\n\n\n\n\n\n\n\n\n\n\n
      Funkcia<\/span><\/span><\/th>\n\u0160pecifik\u00e1cia<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n
      N\u00e1zov produktu<\/span><\/span><\/td>\nKlonazolam 0,6 mg pelety<\/span><\/span><\/td>\n<\/tr>\n
      Balenie<\/span><\/span><\/td>\nBlister s 10 peletami<\/span><\/span><\/td>\n<\/tr>\n
      Formul\u00e1r<\/span><\/span><\/td>\nLisovan\u00e9 pelety<\/span><\/span><\/td>\n<\/tr>\n
      D\u00e1vkovanie<\/span><\/span><\/td>\n0,6 mg na peletu<\/span><\/span><\/td>\n<\/tr>\n
      \u010cistota<\/span><\/span><\/td>\n\u226599% (potvrden\u00e9 HPLC)<\/span><\/span><\/td>\n<\/tr>\n
      Podmienky skladovania<\/span><\/span><\/td>\nChladn\u00e9, such\u00e9, tmav\u00e9<\/span><\/span><\/td>\n<\/tr>\n
      Pou\u017eitie<\/span><\/span><\/td>\nLen na analytick\u00fd v\u00fdskum<\/span><\/span><\/td>\n<\/tr>\n
      Pr\u00e1vne postavenie<\/span><\/span><\/td>\nZ\u00e1vis\u00ed od regi\u00f3nu<\/span><\/span><\/td>\n<\/tr>\n
      Certifik\u00e1t pravosti<\/span><\/span><\/td>\n\u00c1no, na po\u017eiadanie<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

       <\/p>","protected":false},"excerpt":{"rendered":"

      Vlastnosti peliet klonazolamu<\/span><\/span><\/h2>\n

      Synonymum:<\/span><\/span><\/strong> 6-(2-chl\u00f3rfenyl)-1-metyl-8-nitro-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazep\u00edn <\/span><\/span>
      \n\u010c\u00edslo CAS:<\/span><\/span><\/strong> 33887-02-4 <\/span><\/span>
      \nVzorec:<\/span><\/span><\/strong> C17H12C1N5O2 <\/span><\/span>
      \nMol\u00e1rna hmotnos\u0165:<\/span><\/span><\/strong> 353,8 g\/mol <\/span><\/span>
      \n\u010cistota:<\/span><\/span><\/strong> \u226598%<\/span><\/span><\/p>","protected":false},"featured_media":29014,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[488],"product_tag":[326],"class_list":{"0":"post-23688","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-verboden","7":"product_tag-nl","9":"first","10":"outofstock","11":"taxable","12":"shipping-taxable","13":"purchasable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product\/23688","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/comments?post=23688"}],"version-history":[{"count":5,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product\/23688\/revisions"}],"predecessor-version":[{"id":29021,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product\/23688\/revisions\/29021"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/media\/29014"}],"wp:attachment":[{"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/media?parent=23688"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product_brand?post=23688"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product_cat?post=23688"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/sk\/wp-json\/wp\/v2\/product_tag?post=23688"}],"curies":[{"name":"pracovn\u00fd list","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}