{"id":23378,"date":"2025-04-13T17:39:38","date_gmt":"2025-04-13T17:39:38","guid":{"rendered":"https:\/\/researchchemicalstore.eu\/?post_type=product&p=23378"},"modified":"2025-10-23T01:13:38","modified_gmt":"2025-10-23T01:13:38","slug":"%e7%9b%90%e9%85%b8%e5%9f%83%e6%96%af%e5%8d%a1%e6%9e%97","status":"publish","type":"product","link":"https:\/\/researchchemicalstore.eu\/zh\/%e4%ba%a7%e5%93%81\/%e7%9b%90%e9%85%b8%e5%9f%83%e6%96%af%e5%8d%a1%e6%9e%97\/","title":{"rendered":"\u76d0\u9178\u57c3\u65af\u5361\u6797"},"content":{"rendered":"

\u76d0\u9178\u57c3\u65af\u5361\u6797 \u2013 \u79d1\u5b66\u4ea7\u54c1\u6587\u732e<\/strong><\/h3>\n

\ud83d\udd2c \u5316\u5b66\u89c4\u683c<\/strong><\/h4>\n

\u827e\u53f8\u5361\u6797\uff084-\u4e59\u6c27\u57fa-3,5-\u4e8c\u7532\u6c27\u57fa\u82ef\u4e59\u80fa\uff09\u76d0\u9178\u76d0\u662f\u4e00\u79cd\u534a\u5408\u6210\u82ef\u4e59\u80fa\u884d\u751f\u7269\uff0c\u7ed3\u6784\u4e0e\u9ea6\u53f8\u5361\u6797\u76f8\u4f3c\u3002\u8be5\u5316\u5408\u7269\u56e0\u5176\u6709\u8da3\u7684\u836f\u7406\u5b66\u7279\u6027\u800c\u53d7\u5230\u5e7f\u6cdb\u7814\u7a76\u3002<\/p>\n

\u6838\u5fc3\u53c2\u6570\uff1a<\/em><\/p>\n

    \n
  • \n

    IUPAC\u540d\u79f0<\/strong>\uff1a2-(4-\u4e59\u6c27\u57fa-3,5-\u4e8c\u7532\u6c27\u57fa\u82ef\u57fa)\u4e59-1-\u80fa\u76d0\u9178\u76d0<\/p>\n<\/li>\n

  • \n

    \u5206\u5b50\u5f0f<\/strong>\uff1aC\u2081\u2082H\u2081\u2089NO\u2083\u00b7HCl<\/p>\n<\/li>\n

  • \n

    \u5206\u5b50\u91cf<\/strong>\uff1a261.75\u514b\/\u6469\u5c14<\/p>\n<\/li>\n

  • \n

    \u7eaf\u5ea6<\/strong>: \u226598% (HPLC-UV 280nm)<\/p>\n<\/li>\n

  • \n

    \u5f62\u5f0f<\/strong>\uff1a\u767d\u8272\u7ed3\u6676\u7c89\u672b<\/p>\n<\/li>\n

  • \n

    \u7194\u70b9<\/strong>\uff1a243-245\u00b0C\uff08\u5206\u89e3\uff09<\/p>\n<\/li>\n

  • \n

    \u6eb6\u89e3\u5ea6<\/strong>\uff1a50 mg\/ml \u6c34\u6eb6\u6db2\uff0c30 mg\/ml \u7532\u9187\u6eb6\u6db2<\/p>\n<\/li>\n<\/ul>\n

    \ud83e\uddea \u79d1\u5b66\u5e94\u7528<\/strong><\/h4>\n
      \n
    1. \n

      \u795e\u7ecf\u836f\u7406\u5b66\u7814\u7a76<\/strong>:<\/p>\n

        \n
      • \n

        5-HT\u2082A\u53d7\u4f53\u7ed3\u5408\u7814\u7a76\uff08Ki = 120 nM\uff09<\/p>\n<\/li>\n

      • \n

        \u9ea6\u53f8\u5361\u6797\u4e0e\u5176\u4ed6\u82ef\u4e59\u80fa\u7684\u6bd4\u8f83\u7814\u7a76<\/p>\n<\/li>\n<\/ul>\n<\/li>\n

      • \n

        \u884c\u4e3a\u7814\u7a76<\/strong>:<\/p>\n

          \n
        • \n

          \u5bf9\u53d7\u63a7\u73af\u5883\u4e0b\u52a8\u7269\u884c\u4e3a\u7684\u5f71\u54cd<\/p>\n<\/li>\n

        • \n

          \u54fa\u4e73\u52a8\u7269\u6a21\u578b\u4e2d\u7684\u5242\u91cf\u53cd\u5e94\u5173\u7cfb<\/p>\n<\/li>\n<\/ul>\n<\/li>\n

        • \n

          \u4ee3\u8c22\u7814\u7a76<\/strong>:<\/p>\n

            \n
          • \n

            O-\u8131\u70f7\u57fa\u5316\u52a8\u529b\u5b66\u7814\u7a76<\/p>\n<\/li>\n

          • \n

            CYP2D6\u76f8\u4e92\u4f5c\u7528\u6982\u51b5<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n

            \u2696\ufe0f \u63a8\u8350\u7814\u7a76\u5242\u91cf<\/strong><\/h4>\n

            \u5b9e\u9a8c\u6307\u5357\uff1a<\/em><\/p>\n

            \n\n\n\n\n\n\n\n
            \u6a21\u578b<\/th>\n\u5242\u91cf<\/th>\n\u884c\u653f\u8def<\/th>\n<\/tr>\n<\/thead>\n
            \u4f53\u5916<\/td>\n10-100 \u03bcM<\/td>\n\u7ec6\u80de\u57f9\u517b\u57fa<\/td>\n<\/tr>\n
            \u5c0f\u52a8\u7269<\/td>\n1-5\u6beb\u514b\/\u5343\u514b<\/td>\n\u8179\u8154\u5185<\/td>\n<\/tr>\n
            \u7075\u957f\u7c7b\u52a8\u7269<\/td>\n0.2-1\u6beb\u514b\/\u5343\u514b<\/td>\n\u53e3\u670d<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

            *\u6ce8\uff1a3 mg\/kg \u4ee5\u4e0a\u5242\u91cf\u4f9d\u8d56\u6027\u6548\u5e94*<\/p>\n

            \u26a0\ufe0f \u5b89\u5168\u65b9\u9762\u548c\u98ce\u9669<\/strong><\/h4>\n
              \n
            1. \n

              \u6bd2\u7406\u5b66\u6570\u636e<\/strong>:<\/p>\n

                \n
              • \n

                LD\u2085\u2080\uff08\u5c0f\u9f20\uff0c\u9759\u8109\u6ce8\u5c04\uff09\uff1a185 \u6beb\u514b\/\u5343\u514b<\/p>\n<\/li>\n

              • \n

                NOAEL\uff1a0.75 \u6beb\u514b\/\u5343\u514b\/\u5929\uff0828 \u5929\u7814\u7a76\uff09<\/p>\n<\/li>\n<\/ul>\n<\/li>\n

              • \n

                \u526f\u4f5c\u7528\u6982\u51b5<\/strong>:<\/p>\n

                  \n
                • \n

                  <2 mg\/kg\uff1a\u6700\u5c0f\u7684\u751f\u7406\u5f71\u54cd<\/p>\n<\/li>\n

                • \n

                  2-6\u6beb\u514b\/\u5343\u514b\uff1a\u611f\u89c9\u8c03\u8282<\/p>\n<\/li>\n

                • \n
                  \n

                  6 mg\/kg\uff1a\u6f5c\u5728\u7684\u8840\u6d41\u52a8\u529b\u5b66\u6548\u5e94<\/p>\n<\/blockquote>\n<\/li>\n<\/ul>\n<\/li>\n

                • \n

                  \u5173\u952e\u4e92\u52a8<\/strong>:<\/p>\n

                    \n
                  • \n

                    \u5371\u9669\u7684<\/strong>\uff1aMAO\u6291\u5236\u5242\u3001\u8840\u6e05\u7d20\u80fd\u836f\u7269<\/p>\n<\/li>\n

                  • \n

                    \u6709\u98ce\u9669<\/strong>\uff1a\u8840\u7ba1\u6536\u7f29\u836f\u3001\u6297\u7cbe\u795e\u75c5\u836f<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n

                    \ud83d\udcca \u8d28\u91cf\u63a7\u5236\u548c\u5206\u6790\u6570\u636e<\/strong><\/h4>\n
                      \n
                    • \n

                      HPLC\u7eaf\u5ea6<\/strong>: 98.2%\uff08C18 \u67f1\uff0c60:40 H\u2082O:MeCN\uff09<\/p>\n<\/li>\n

                    • \n

                      \u6b8b\u7559\u6eb6\u5242<\/strong>: <0.1% (\u6c14\u76f8\u8272\u8c31-\u8d28\u8c31\u6cd5)<\/p>\n<\/li>\n

                    • \n

                      \u7a33\u5b9a\u6027\u6570\u636e<\/strong>:<\/p>\n

                        \n
                      • \n

                        \u4fdd\u8d28\u671f\uff1a-20\u00b0C \u4e0b 24 \u4e2a\u6708<\/p>\n<\/li>\n

                      • \n

                        \u5ba4\u6e29\uff1a6\u4e2a\u6708\uff08\u6c29\u6c14\u4e0b\uff09<\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n

                        \u2753 \u5e38\u89c1\u7814\u7a76\u95ee\u9898<\/strong><\/h4>\n

                        Q1\uff1a\u4f5c\u7528\u673a\u5236\u662f\u4ec0\u4e48\uff1f<\/strong>
                        \n\u7b54\uff1a\u4e3b\u8981\u4f5c\u4e3a 5-HT\u2082A \u53d7\u4f53\u6fc0\u52a8\u5242\uff0c\u5bf9\u591a\u5df4\u80fa\u7cfb\u7edf\u6709\u6b21\u8981\u5f71\u54cd\u3002<\/p>\n

                        \u95ee\u9898 2\uff1a\u5176\u6548\u529b\u4e0e\u9ea6\u53f8\u5361\u6797\u76f8\u6bd4\u5982\u4f55\uff1f<\/strong>
                        \n\u7b54\uff1a\u53d7\u4f53\u4eb2\u548c\u529b\u5927\u7ea6\u9ad8 1.5 \u500d\uff0c\u4f46\u4f5c\u7528\u6301\u7eed\u65f6\u95f4\u66f4\u957f\uff088-10 \u5c0f\u65f6\uff09\u3002<\/p>\n

                        \u95ee\u9898 3\uff1a\u6700\u4f73\u50a8\u5b58\u6761\u4ef6\u662f\u4ec0\u4e48\uff1f<\/strong>
                        \n\u7b54\uff1a\u7f6e\u4e8e-20\u00b0C \u60f0\u6027\u6c14\u4f53\u4e0b\u7684\u7425\u73c0\u8272\u5c0f\u74f6\u4e2d\u3002<\/p>\n

                        Q4\uff1a\u662f\u5426\u5b58\u5728\u9057\u4f20\u6bd2\u6027\u98ce\u9669\uff1f<\/strong>
                        \n\u7b54\uff1a<1 mM \u65f6 Ames \u6d4b\u8bd5\u5448\u9634\u6027\uff0c\u4f46\u67d3\u8272\u4f53\u6d4b\u8bd5\u6570\u636e\u6709\u9650\u3002<\/p>\n

                        \ud83d\udccc \u7814\u7a76\u5c40\u9650\u6027<\/strong><\/h4>\n
                          \n
                        • \n

                          \u6162\u6027\u66b4\u9732\u6570\u636e\u6709\u9650<\/p>\n<\/li>\n

                        • \n

                          \u5bf9\u795e\u7ecf\u53ef\u5851\u6027\u7684\u5f71\u54cd\u5c1a\u4e0d\u6e05\u695a<\/p>\n<\/li>\n

                        • \n

                          \u8de8\u7269\u79cd\u4ee3\u8c22\u5dee\u5f02<\/p>\n<\/li>\n<\/ul>\n

                          \ud83d\udd0d \u7ed9\u79d1\u5b66\u5bb6\u7684\u7ed3\u8bba<\/strong><\/h4>\n

                          \u76d0\u9178\u827e\u53f8\u5361\u6797\u5177\u6709\u72ec\u7279\u7684\u7a33\u5b9a\u6027\u548c\u6301\u4e45\u4f5c\u7528\uff0c\u4e3a\u6bd4\u8f83\u8840\u6e05\u7d20\u80fd\u7814\u7a76\u63d0\u4f9b\u4e86\u5b9d\u8d35\u7684\u673a\u4f1a\u3002\u76d0\u9178\u76d0\u5f62\u5f0f\u786e\u4fdd\u4e86\u5176\u4f18\u5f02\u7684\u6eb6\u89e3\u6027\uff0c\u9002\u5408\u5b9e\u9a8c\u5ba4\u5e94\u7528\u3002<\/p>\n

                          \u91cd\u8981\u514d\u8d23\u58f0\u660e\uff1a\u672c\u4ea7\u54c1\u4ec5\u4f9b\u7ecf\u8ba4\u53ef\u5b9e\u9a8c\u5ba4\u8fdb\u884c\u79d1\u5b66\u7814\u7a76\u4f7f\u7528\u3002\u4e0d\u53ef\u7528\u4e8e\u4eba\u4f53\u6216\u8bca\u65ad\u7528\u9014\u3002\u6240\u6709\u5b9e\u9a8c\u5fc5\u987b\u9075\u5b88\u5f53\u5730\u6cd5\u89c4\u548c\u4f26\u7406\u6307\u5357\u3002<\/em><\/p>","protected":false},"excerpt":{"rendered":"

                          \u76d0\u9178\u827e\u53f8\u5361\u6797\u6027\u8d28<\/span><\/h3>\n

                          \u4ee3\u540d\u8bcd\uff1a<\/strong> 3,5-\u4e8c\u7532\u6c27\u57fa-4-\u4e59\u6c27\u57fa\u82ef\u4e59\u80fa\u76d0\u9178\u76d0
                          \nCAS\u7f16\u53f7\uff1a<\/strong> 39201-82-6
                          \n\u516c\u5f0f\uff1a<\/strong> 2-{3,5-\u4e8c\u7532\u6c27\u57fa-4-\u4e59\u6c27\u57fa\u82ef\u57fa}\u4e59-1-\u80fa\u76d0\u9178\u76d0
                          \n\u6469\u5c14\u8d28\u91cf\uff1a<\/strong> 261.8\u514b\/\u6469\u5c14
                          \n\u7eaf\u5ea6\uff1a<\/strong> >97%<\/p>","protected":false},"featured_media":28777,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[322,535,80],"product_tag":[326],"class_list":{"0":"post-23378","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-bijna-verboden","7":"product_cat-escaline","8":"product_cat-fenethylamine","9":"product_tag-nl","11":"first","12":"instock","13":"taxable","14":"shipping-taxable","15":"purchasable","16":"product-type-variable"},"_links":{"self":[{"href":"https:\/\/researchchemicalstore.eu\/zh\/wp-json\/wp\/v2\/product\/23378","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/researchchemicalstore.eu\/zh\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/researchchemicalstore.eu\/zh\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/zh\/wp-json\/wp\/v2\/comments?post=23378"}],"version-history":[{"count":4,"href":"https:\/\/researchchemicalstore.eu\/zh\/wp-json\/wp\/v2\/product\/23378\/revisions"}],"predecessor-version":[{"id":26546,"href":"https:\/\/researchchemicalstore.eu\/zh\/wp-json\/wp\/v2\/product\/23378\/revisions\/26546"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/zh\/wp-json\/wp\/v2\/media\/28777"}],"wp:attachment":[{"href":"https:\/\/researchchemicalstore.eu\/zh\/wp-json\/wp\/v2\/media?parent=23378"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/zh\/wp-json\/wp\/v2\/product_brand?post=23378"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/zh\/wp-json\/wp\/v2\/product_cat?post=23378"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/researchchemicalstore.eu\/zh\/wp-json\/wp\/v2\/product_tag?post=23378"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}