Tropacocaine HCl

Product Definition: Tropacocaine HCl (Research Chemical)

Chemical Name:  Tropacocaine hydrochloride
Synonyms:  Tropacocaine HCl, Benzoylecgonine methyl ester
Molecular Formula:  C₁₅H₁₉NO₂•HCl
Molecular Weight:  281.78 g/mol
CAS No.:  537-26-8
Appearance:  White crystalline powder
Purity:  ≥98% (HPLC verified)
Solubility:  50 mg/ml in water

Description & Pharmacology:
Tropacocaine is a naturally occurring cocaine analog with:
✔Local anesthetic effects
✔Stimulant properties
✔Shorter duration of action than cocaine (1-2 hours)
✔More selective noradrenaline reuptake inhibition

Research applications:

1. Neuroscience research:

   • Dopamine transporter studies

   • Comparative pharmacology of stimulants

2. Medical examination:

   • Local anesthetic mechanisms

   • Vasoconstriction studies

3. Analytical chemistry:

   • Reference standard for drug analysis

   • Forensic investigation

Benefits for Research:
✅ Naturally occurring compound
✅Less addiction potential than cocaine
✅Good stability in solution
✅Suitable for in vitro receptor studies

Risks & Limitations:
❌ Possible side effects:

• Tachycardia

• Hypertension

• CNS stimulation
  ❌Limited pharmacokinetic data available
  ❌Potential for abuse

Dosage protocol (for research):

Safety measures:

• Wear appropriate PPE (gloves, lab coat)

• Work under a fume hood

• Avoid contact with skin and eyes

• Do not combine with MAO inhibitors

Frequently Asked Questions:

1. Is Tropacocaine legal in the Netherlands?
   It may fall under the Opium Act as a cocaine-related substance.

2. How is it different from cocaine?
   Less euphoric effect, shorter duration of action.

3. Can it be used as a local anesthetic?
   For research purposes only, not for medical use.

4. Is it detectable on drug tests?
   It may cross-react with cocaine tests.

Quality Control & Analytical Data:

Specifications:

• Purity: ≥98% (HPLC)

• Heavy metals: <1 ppm

• Loss on drying: <0.5%

• Residual solvents: <0.1%

Stability data:

• Shelf life: 36 months at 15-25°C

• Light sensitivity: Moderate

• Moisture sensitivity: High

Conclusion:
Tropacocaine HCl is a valuable research substance for pharmacological and analytical studies, but requires responsible use.

⚠ For research purposes only – not for human use

Storage advice:

• Airtight packaging

• Store in a dark place

• Dry at <25°C

Ethical considerations:

• For use by qualified personnel only

• Animal testing requires ethical approval

• Document all experiments accurately