盐酸托可卡因

Product Definition: Tropacocaine HCl (Research Chemical)

化学名称：  Tropacocaine hydrochloride
同义词：  Tropacocaine HCl, Benzoylecgonine methyl ester
分子式：  C₁₅H₁₉NO₂•HCl
分子量：  281.78 g/mol
CAS编号：  537-26-8
外貌：  白色结晶粉末
纯度：  ≥98%（HPLC验证）
溶解度：  50毫克/毫升水溶液

描述和药理学：
Tropacocaine is a naturally occurring cocaine analog with:
✔Local anesthetic effects
✔Stimulant properties
✔Shorter duration of action than cocaine (1-2 hours)
✔More selective noradrenaline reuptake inhibition

研究应用：

1. 神经科学研究：

   • 多巴胺转运体研究

   • Comparative pharmacology of stimulants

2. Medical examination:

   • Local anesthetic mechanisms

   • Vasoconstriction studies

3. 分析化学：

   • Reference standard for drug analysis

   • Forensic investigation

对研究的益处：
✅ Naturally occurring compound
✅Less addiction potential than cocaine
✅Good stability in solution
✅Suitable for in vitro receptor studies

风险与限制：
❌ 可能的副作用：

• 心动过速

• 高血压

• CNS stimulation
  ❌Limited pharmacokinetic data available
  ❌Potential for abuse

剂量方案（用于研究）：

安全措施：

• Wear appropriate PPE (gloves, lab coat)

• Work under a fume hood

• 避免接触皮肤和眼睛

• Do not combine with MAO inhibitors

常见问题：

1. Is Tropacocaine legal in the Netherlands?
   It may fall under the Opium Act as a cocaine-related substance.

2. How is it different from cocaine?
   Less euphoric effect, shorter duration of action.

3. Can it be used as a local anesthetic?
   For research purposes only, not for medical use.

4. Is it detectable on drug tests?
   It may cross-react with cocaine tests.

质量控制和分析数据：

规格：

• 纯度：≥98%（HPLC）

• Heavy metals: <1 ppm

• Loss on drying: <0.5%

• 残留溶剂：<0.1%

稳定性数据：

• Shelf life: 36 months at 15-25°C

• 光敏感度：中等

• 湿气敏感度：高

结论：
Tropacocaine HCl is a valuable research substance for pharmacological and analytical studies, but requires responsible use.

⚠ For research purposes only – not for human use

储存建议：

• 密封包装

• 存放在阴暗处

• 干燥温度低于 25°C

道德考虑：

• For use by qualified personnel only

• 动物试验需要伦理批准

• Document all experiments accurately